Results 61 to 70 of about 803,904 (364)

Developing An Analytic Approach to Understanding the Patient Care Experience

Journal of Patient Experience, 2016
The amount of data available to health-care institutions regarding the patient care experience has grown tremendously. Purposeful approaches to condensing, interpreting, and disseminating these data are becoming necessary to further understand how ...
Mary Kate Springman MHA, Yalissa Bermeo MBA, Heather M Limper MPH, Alison S Tothy MD   +3 more
doaj   +1 more source

Variation in parental experiences with their child’s hospitalization over the COVID-19 pandemic

Journal of Patient-Reported Outcomes, 2023
Background Hospitals and healthcare workers have been greatly impacted by the COVID-19 pandemic. The potential impacts upon the patient experience have been less documented, particularly in the pediatric setting.
Kyle A. Kemp, Paul Fairie, Brian Steele, Maria J. Santana   +3 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Protocol for the development of guidance for stakeholder engagement in health and healthcare guideline development and implementation [PDF]

, 2020
Stakeholder engagement has become widely accepted as a necessary component of guideline development and implementation. While frameworks for developing guidelines express the need for those potentially affected by guideline recommendations to be involved
Akl, Elie A., Atwere, Pearl, Campbell, Pauline, Chalkidou, Kalipso, Chang, Stephanie M., Concannon, Thomas W., Crowe, Sally, Dans, Leonila, El Jardali, Fadi, Ghersi, Davina, Graham, Ian D., Grant, Sean, Greer-Smith, Regina, Guise, Jeanne-Marie, Hazlewood, Glen, Jull, Janet, Katikireddi, S. Vittal, Khabsa, Joanne, Langlois, Etienne V., Lyddiatt, Anne, Lytvyn, Lyubov, Maxwell, Lara, Morley, Richard, Mustafa, Reem A., Nonino, Francesco, Pardo, Jordi Pardo, Petkovic, Jennifer, Pollock, Alex, Pottie, Kevin, Riddle, Alison, Riva, John, Schünemann, Holger, Simeon, Rosiane, Smith, Maureen, Stein, Airton T., Synnot, Anneliese, Tufte, Janice, Tugwell, Peter, Welch, Vivian, White, Howard   +39 more
core   +3 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Meaningful patient engagement [PDF]

BJPsych Advances, 2018
SUMMARYHolding a medical degree does not magically protect the individual from ever becoming unwell or needing medical help. However, for various reasons, most of which relate to personal, professional and institutional stigma, doctors are often denied the care they so readily provide to their own patients.
openaire   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

Testing the Healthcare Complaints Analysis Tool in a Specialist Pediatric Hospital to Assess Potential Utility for Organizational Learning from Complaints

Journal of Patient Experience, 2022
The importance of improving the analysis of complaints about poor healthcare experiences is recognized but often not addressed. We explored the utility of the Healthcare Complaints Assessment Tool for analyzing written complaints in a specialist ...
Jo Wray PhD, Claire Williams BA, Geralyn Oldham MSc   +2 more
doaj   +1 more source

Non–Small Cell Lung Cancer Symptom Assessment Questionnaire: Psychometric Performance and Regulatory Qualification of a Novel Patient-Reported Symptom Measure

Current Therapeutic Research, 2021
: Background: The Non–Small Cell Lung Cancer Symptom Assessment Questionnaire (NSCLC-SAQ) was developed to incorporate the patient's perspective into evaluation of clinical benefit in advanced non–small cell lung cancer trials and meet regulatory ...
Donald M. Bushnell, MA, Thomas M. Atkinson, PhD, Kelly P. McCarrier, PhD, Astra M. Liepa, PharmD, Kendra P. DeBusk, PhD, Stephen Joel Coons, PhD   +5 more
doaj   +1 more source

The impact of a night confinement policy on patients in a high secure inpatient mental health service. [PDF]

, 2015
Purpose – From 2012, all high-secure forensic mental health services in England began operating a policy of confining patients to their locked bedrooms overnight to increase service efficiency and reduce costs.
Chu, Simon, Hague, Anthony, McNeill, Kimberley, Wilkins, Tracy, Wright, Karen Margaret   +4 more
core   +1 more source