Results 101 to 110 of about 1,982,576 (303)

The nursing contribution to chronic disease management: a whole systems approach: Report for the National Institute for Health Research Service Delivery and Organisation programme [PDF]

open access: yes, 2010
Background Transforming the delivery of care for people with Long Term Conditions (LTCs) requires understanding about how health care policies in England and historical patterns of service delivery have led to different models of chronic disease ...
Brooks, Fiona   +6 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Digital room-layout planning for complex manual handling hospital discharges

open access: yesInternational Journal of Integrated Care, 2014
Brian Bernard Abraham   +2 more
doaj   +3 more sources

Facilitating consumer partnerships in health research

open access: yesJournal of Translational Medicine
Background Consumer engagement and involvement in health research is a well-established and growing priority for a better-informed public, a broader voice for research in relation to impact and funding, and guidance toward issues that matter most to ...
Raluca Ghebosu   +8 more
doaj   +1 more source

Patient-Centred Design of Healthcare Services: Meaningful Events as Basis for Patient Experiences of Families

open access: yes, 2017
Patient experience has become a crucial part of the quality of any healthcare service. Experiences and their structures are not however trivial phenomena that are easy to describe and model. Instead, subjective and dynamic experiences seem to escape definitions and measurements.
Kaipio Johanna   +2 more
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Improving healthcare services for living kidney donors: an experience-based approach in the Netherlands

open access: yesFrontiers in Public Health
Living kidney donors voluntarily donate one of their kidneys to someone suffering from end-stage kidney disease. Transplantation is a life-saving opportunity for these patients and generally provides an increase in quality of life.
Wim S. Sipma   +4 more
doaj   +1 more source

How patients' experiences help institutions to improve care in oncological pathway. [PDF]

open access: yes
To improve services, institutions need to listen the patients voice. The patient experience through the health care pathway can help institutions to point out the problems and to learn to design the organization putting the patient at the center of the ...
Enrico Desideri   +3 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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