Results 111 to 120 of about 1,982,576 (303)
Co‐Designing Solutions to Improve Communication About Serious Illness During Hospitalisation
Health ExpectationsBackground Serious illness conversations (SICs) that explore patient priorities are becoming increasingly important to high‐quality care for those with life‐limiting conditions admitted to general internal medicine wards.
Isabelle Caven +11 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
The Healing Pathway in Hospital Design: The Role of Hospital Structural Elements in Shaping Patient Experience and Implicit Healthcare Marketing [PDF]
Rāhburdhā-yi Mudīriyyat dar Niẓām-i SalāmatThe health facility environment is more than a backdrop to care; it is a key contributor to the quality of health care as perceived by patients. Evidence-based design—through lighting, layout, and wayfinding—reduces stress, enhances safety, and boosts ...
Fahimeh Shojaeifar
doaj
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
A new approach to planning in vitro and in vivo experiments for cardiovascular stents – II. Planning of experiment (abstract) [PDF]
, 2000 Within our overall project to improve the design of stents in terms of reduced rates of re-stenosis, there are three main methods, namely computer simulation and in vitro and in vivo experiments.
Atherton, M, Collins, MW, Doorly, DJ
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Digital First: Community Health & Wellbeing project (An NHS England widening participation flagship)
International Journal of Integrated Care, 2014 Charlie Young
doaj +3 more sources
User Experience Development in Elderly Heart Patient Monitoring System
Jurnal Nasional Teknik Elektro dan Teknologi InformasiHeart disease is a major global cause of death, particularly among the elderly. Elderly often face challenges in accessing healthcare due to physical and cognitive limitations, making remote health monitoring systems a crucial solution.
Alaric Rasendriya Aniko +3 more
doaj +1 more source