Results 11 to 20 of about 4,197,993 (309)

Patient-centered endodontic outcomes: a narrative review. [PDF]

, 2013
IntroductionRoot canal treatment (RCT) success criteria inform us of the path to bony healing and of prognostic factors, but tell little about how the patient perceives, feels, or values RCT.
Fayazi, Sara, Hamedy, Reza, Pak, Jacklyn G, Shakiba, Bita, White, Shane N   +4 more
core   +3 more sources

How to address the challenges of evaluating treatment benefits-risks in rare diseases? A convergent mixed methods approach applied within a Merkel cell carcinoma phase 2 clinical trial

Orphanet Journal of Rare Diseases, 2018
Background Demonstrating treatment benefits within clinical trials in the context of rare diseases is often methodologically and practically challenging. Mixed methods research offers an approach to overcome these challenges by combining quantitative and
Murtuza Bharmal, Isabelle Guillemin, Alexia Marrel, Benoit Arnould, Jérémy Lambert, Meliessa Hennessy, Fatoumata Fofana   +6 more
doaj   +1 more source

Generation of evidence supporting the content validity of SF-36, FACIT-F, and LupusQoL, and novel patient-reported symptom items for use in patients with systemic lupus erythematosus (SLE) and SLE with lupus nephritis (LN)

Lupus Science and Medicine, 2022
Objective SLE and lupus nephritis (LN) have significant impacts on the health-related quality of life of patients living with the condition, which are important to capture from the patient’s perspective using patient-reported outcomes (PROs).
Vibeke Strand, Anna Roberts, Zahi Touma, Amy Ward, Pamela Berry, Rebecca Williams-Hall, Nicola Williamson, Melissa Barclay, Adam Gater, Chloe Tolley, Helena Bradley, Elizabeth Hsia, Qing Zuraw, Patricia DeLong   +13 more
doaj   +1 more source

When Patient Activation Levels Change, Health Outcomes and Costs Change, Too [PDF]

, 2015
Patient engagement has become a major focus of health reform. However, there is limited evidence showing that increases in patient engagement are associated with improved health outcomes or lower costs.
Carmen D. Parrotta, Jessica Greene, Judith H. Hibbard, Rebecca Sacks, Valerie Overton   +4 more
core   +1 more source

Patient experience of moderate asthma attacks: qualitative research in the USA and Germany

Journal of Patient-Reported Outcomes, 2022
Background There is limited information available on the impact of moderate asthma exacerbations, often called “asthma attacks” (i.e., those not requiring hospitalisation or treatment with systemic corticosteroids) on patients’ lives.
Maggie Tabberer, Jane R. Wells, Dale Chandler, Linda Abetz-Webb, Shiyuan Zhang, Wilhelmine Meeraus, Andy Fowler, David Slade   +7 more
doaj   +1 more source

Psychometric properties of the FACT-M questionnaire in patients with Merkel cell carcinoma

Health and Quality of Life Outcomes, 2017
Background No validated disease-specific questionnaires exist to capture health-related quality of life (HRQoL) in patients with Merkel cell carcinoma (MCC).
Murtuza Bharmal, Fatoumata Fofana, Carla Dias Barbosa, Paul Williams, Lisa Mahnke, Alexia Marrel, Michael Schlichting   +6 more
doaj   +1 more source

Use of the European Organisation for Research and Treatment of Cancer multiple myeloma module (EORTC QLQ-MY20): a review of the literature 25 years after development

Blood Cancer Journal, 2023
The European Organisation for Research and Treatment of Cancer Quality of Life Multiple Myeloma Questionnaire (EORTC QLQ-MY20) was developed in 1996 to assess health-related quality of life (HRQoL) in patients with multiple myeloma. Since its development
K. Forde, K. Cocks, J. R. Wells, I. McMillan, C. Kyriakou, EORTC Quality of Life Group   +5 more
doaj   +1 more source

Correction to: Psychometric properties of the FACT-M questionnaire in patients with Merkel cell carcinoma

Health and Quality of Life Outcomes, 2019
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Murtuza Bharmal, Fatoumata Fofana, Carla Dias Barbosa, Paul Williams, Lisa Mahnke, Alexia Marrel, Michael Schlichting   +6 more
doaj   +1 more source

To what degree are orphan drugs patient-centered? A review of the current state of clinical research in rare diseases

Orphanet Journal of Rare Diseases, 2020
Background Over the past 30 years, the healthcare industry has increasingly turned its attention to rare diseases. Regulators have emphasized the need for clinical research in this area to be patient-centered.
Sally Lanar, Catherine Acquadro, James Seaton, Isabelle Savre, Benoit Arnould   +4 more
doaj   +1 more source

Development and content validity assessment of the Dry Eye Disease Questionnaire in patients with dry eye disease, meibomian gland dysfunction, and Sjögren’s syndrome dry eye disease

Journal of Patient-Reported Outcomes, 2023
Background Dry eye disease (DED), Meibomian gland dysfunction (MGD), and Sjögren’s syndrome dry eye disease (SS-DED) are eye dryness conditions that show significant overlap in various symptoms of ocular discomfort.
Brigitte Sloesen, Alyson Young, Katie Forde, Nicola Hodson, Sarah Bentley, Oonagh Walsh, Christel Naujoks, Paul O’Brien, Garima Sharma   +8 more
doaj   +1 more source