Results 201 to 210 of about 2,860,764 (308)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Self-completed patient-reported outcome measures in adults with epilepsy: A review. [PDF]

Epilepsia Open
Conquest AL, O'Brien TJ, Kwan P, French JA, Malpas CB, Foster EC.   +5 more
europepmc   +1 more source

Assessing patient reported outcome measures: A practical guide for gastroenterologists [PDF]

, 2014
Bombardier C, Devlin NJ, Deyo RA, Domino G, Drossman DA, Masachs M, Mouzas IA, Muller S, Murphy KaCD, Nightingale F, Spaccavento S, Vandenberghe A, Verissimo R   +12 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Persistent Postmastectomy Pain: A Comparison of Diagnosis and Patient-reported Outcome Measures in 6988 Patients. [PDF]

Plast Reconstr Surg Glob Open
Rochlin DH, Levy J, Kim M, Boe L, Mehrara BJ, Nelson JA.   +5 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

A comparison of in-the-moment and retrospective patient-reported outcome measures in advanced cancer. [PDF]

Support Care Cancer
Geeraerts J, de Nooijer K, Pivodic L, Crombez G, Decoster L, Fontaine C, Joris S, Naert E, De Ridder M, Van den Block L.   +9 more
europepmc   +1 more source

Patient-Reported Outcomes, Patient-Reported Information

The Patient: Patient-Centered Outcomes Research
Baldwin, Mike, Spong, Andrew, Doward, Lynda, Gnanasakthy, Ari   +3 more
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Variation in the feasibility and acceptability of electronic patient-reported outcome measures in patients with inflammatory arthritis. [PDF]

Rheumatol Adv Pract
Cox N, Kettle C, Wang H, Dutta S, Packham J, Galloway J, Hill J, Muller S, Hider S, Paskins Z, Bullock L, Scott IC.   +11 more
europepmc   +1 more source