Results 141 to 150 of about 7,965,138 (244)

Liver Transplantation for HBV-Related Disease in France: NUC Type Before LT Is Associated With Patient Survival. [PDF]

Liver Int
Bienvenue I, Roux O, Coilly A, Abergel A, Antonini T, Artzner T, Boillot O, Chermak F, Conti F, Dharancy S, Duvoux C, Elkrief L, Farrugia M, Francoz C, Giguet B, Hardwigsen J, Houssel-Debry P, Hilleret MN, Kamar N, Latournerie M, Meszaros M, Radenne S, Roche B, Salamé E, Verhoeven-Weil D, Samuel D, Zoulim F, Dumortier J, Villeret F.   +28 more
europepmc   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Coping Strategies and Experiences of Patients With Crohn's Disease During the COVID-19 Epidemic: A Descriptive Phenomenology Study. [PDF]

Nurs Open
Chen D, Mei W, Liu Q, Yu Z, Pan T, Zhang A, Kong F, Chen Y.   +7 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Chronic diseases: 2010–2011 progress of the unit for chronic patients and evidence-based medicine of Donostia Hospital/Patologías crónicas: evolución 2010–2011 de la unidad de crónicos y medicina basada en la evidencia del Hospital Donostia

International Journal of Integrated Care, 2012
Joxe Artetxe, Kepa Aranegi, Mª Isabel Huertas, Jose Emparanza, Iñaki Dorronsoro, Elena Suquía   +5 more
doaj   +3 more sources

Characteristics, management, and outcomes of patients with VIPoma-A retrospective analysis of the ENETS database. [PDF]

J Neuroendocrinol
Bartsch DK, Mais L, de Mestier L, Baudin E, Kaltsas G, Hofland J, Garcia-Carbonero R, Tiensuu Janson E, McNamara MG, Andreassen M, Grozinsky-Glasberg S, Spada F, Leupe H, Panzuto F, Fleschen M, Klinkhammer H.   +15 more
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Prevalence of acute kidney injury in geriatric patients: Equal contribution of arthroplasty and osteosynthesis of the proximal femur. [PDF]

SAGE Open Med
Tara B, Kylies D, Priemel M, Frosch KH, Ballhause TM.   +4 more
europepmc   +1 more source