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Pattern Recognition Receptors in Plant Immunity
Plant innate immunity is an advanced defense system to counteract pathogenic stresses. It relies on the recognition of microbial invasion through cell surface-localized pattern recognition receptors (PRRs) and intracellular nucleotide-binding domain leucine-rich repeat receptors (NLRs).Mughair, Abdul Aziz +2 more
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Therapeutic targeting of pattern-recognition receptors
International Immunopharmacology, 2006Innate immune system could recognize the pathogen-associated molecular patterns by pattern-recognition receptors like Toll-like receptor (TLR) and nucleotide-binding oligomerisation domain (NOD) protein. Information regarding the structure and signalling pathways of TLRs and NODs could provide opportunities for new therapeutic approaches to modulate ...
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Pattern Recognition by NOD-Like Receptors
Nucleotide-binding oligomerization domain-like receptors (NLRs) are a family of cytosolic pattern recognition receptors (PRRs) and able to respond to conserved microbe-associated molecular patterns (MAMPs) and endogenous damage-associated molecular patterns (DAMPs).Timo-Daniel, Voss +2 more
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Autophagy and Pattern Recognition Receptors
2016Autophagy is an evolutionarily conserved eukaryotic process that eliminates intracellular components through lysosomal degradation for recycling. It is a hierarchized multistep process that is involved in a multitude of cellular functions and its fine regulation is required for cell homeostasis as indicated by the various pathologies associated with ...
Christophe Viret, Mathias Faure
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Pattern Recognition Receptors in Autoinflammation
2019The immune system is essential for maintenance of tissue homeostasis. This task requires that immune cells detect and respond to dyshomeostatic states (when homeostasis has broken down) that can occur during invasion of the host with pathogenic microbes, after sterile trauma of tissues or during metabolic derangements.
Saavedra, Victor +3 more
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Pattern Recognition Receptor Antagonism
Science Signaling, 2014A pathogenic fungus activates two C-type lectin receptors to skew the T cell response to one favorable to infection.
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WSA03 ‐ Pattern Recognition Receptors
European Journal of Immunology, 2009AbstractNo ...
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Pattern Recognition Receptors and Aging
2013Pattern recognition receptors (PRRs), such as the toll-like receptors (TLRs), C-type lectin receptors (CLRs), nucleotide-binding oligomerization domain and leucine-rich repeat-containing receptors (NLRs), and the more recently discovered cytosolic RNA- and DNA-sensing receptors, are a crucial element of the innate immune system owing to their function ...
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