Results 121 to 130 of about 74,037 (234)

Loss of function of MusaPUB genes in banana can provide enhanced resistance to bacterial wilt disease

Communications Biology
Plants deploy a sophisticated defense mechanism against pathogens through pattern recognition receptors (PRRs) and resistance (R) proteins, activating pattern-triggered immunity (PTI) and effector-triggered immunity (ETI). E3 ubiquitin ligases, notably U-
Leena Tripathi, Valentine Otang Ntui, Samwel Muiruri, Trushar Shah, Jaindra Nath Tripathi   +4 more
doaj   +1 more source

Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier, Françoise Heran, Francis Lallemand, Pierre Bourdillon   +3 more
wiley   +1 more source

Time-series transcriptome of Brachypodium distachyon during bacterial flagellin-induced pattern-triggered immunity. [PDF]

Front Plant Sci, 2022
Ogasahara T, Kouzai Y, Watanabe M, Takahashi A, Takahagi K, Kim JS, Matsui H, Yamamoto M, Toyoda K, Ichinose Y, Mochida K, Noutoshi Y.   +11 more
europepmc   +1 more source

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science
The flagellin peptide flg22 activates FLAGELLIN‐SENSING 2 (FLS2)‐mediated immunity in Arabidopsis, leading to growth inhibition and oxidative burst. While these responses are well‐studied, their cell‐type‐specific regulation remains poorly understood ...
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
doaj   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source

RING-Type E3 Ubiquitin Ligases AtRDUF1 and AtRDUF2 Positively Regulate the Expression of PR1 Gene and Pattern-Triggered Immunity. [PDF]

Int J Mol Sci, 2022
Yi SY, Lee M, Kwon SY, Kim WT, Lim YP, Kang SY.   +5 more
europepmc   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Chitin Soil Amendment Triggers Systemic Plant Disease Resistance Through Enhanced Pattern-Triggered Immunity. [PDF]

Plant Biotechnol J
Makechemu M, Goto Y, Schmid MW, Zbinden H, Widrig V, Kaufmann M, Pothier JF, Keller B, Zipfel C.   +8 more
europepmc   +2 more sources

In planta transcriptomics reveals conflicts between pattern-triggered immunity and the AlgU sigma factor regulon. [PDF]

PLoS One, 2022
Wang H, Smith A, Lovelace A, Kvitko BH.
europepmc   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source