Results 131 to 140 of about 2,595,399 (242)

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru   +13 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

News from the frontline:recent insights into PAMP-triggered immunity in plants

open access: yes, 2008
Plants have developed a complex defence network to fight off invading pathogens. In recent years, the full importance of pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) within this network became apparent.
Zipfel, Cyril; https://orcid.org/   +2 more
core   +1 more source

Dissecting root-specific non-conventional effector-triggered immunity and its role in defense and shifting the microbiome

open access: yesNature Communications
Plant roots are extremely heterogeneous and non-photosynthetic tissue that is drastically different from leaves. Pioneering studies have revealed the existence of pattern-triggered immune responses in roots; however, whether roots mount tissue-specific ...
Xianli Tang   +7 more
doaj   +1 more source

Multilayer regulatory landscape during pattern-triggered immunity in rice. [PDF]

open access: yesPlant Biotechnol J, 2021
Tang B   +7 more
europepmc   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro   +14 more
wiley   +1 more source

Loss of function of MusaPUB genes in banana can provide enhanced resistance to bacterial wilt disease

open access: yesCommunications Biology
Plants deploy a sophisticated defense mechanism against pathogens through pattern recognition receptors (PRRs) and resistance (R) proteins, activating pattern-triggered immunity (PTI) and effector-triggered immunity (ETI). E3 ubiquitin ligases, notably U-
Leena Tripathi   +4 more
doaj   +1 more source

Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier   +3 more
wiley   +1 more source

Time-series transcriptome of Brachypodium distachyon during bacterial flagellin-induced pattern-triggered immunity. [PDF]

open access: yesFront Plant Sci, 2022
Ogasahara T   +11 more
europepmc   +1 more source

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