Results 81 to 90 of about 476,732 (307)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
, 2005 There has recently been a growing interest in the spatial causes of poverty, particularly in the processes involved in the formation of poverty areas within cities.
Vaughan, L, Clark, DLC, Sahbaz, O
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Multibody dynamics for biologically inspired smart space structure
, 2013 Structures in space are often just serving a single purpose. By developing a structure which is able to change it properties and adapt to changing environmental conditions, the costs of space missions can be decreased significantly.
Sinn, Thomas, Vasile, Massimiliano
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An Ensemble Approach to Space-Time Interpolation [PDF]
There has been much excitement and activity in recent years related to the relatively sudden availability of earth-related data and the computational capabilities to visualize and analyze these data.
Sharolyn Anderson +2 more
core +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
A study of the spatial characteristics of the Jews in London 1695 & 1895
, 1994 This paper suggests that the settlement pattern of Jews in London is in a distinct cluster, but contradicts the accepted belief about the nature of the 'ghetto'; finding that the traditional conception of the 'ghetto', as an enclosed, inward-looking ...
Vaughan, Laura
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Linear and ellipsoidal pattern separation: theoretical aspects and experimental analysis
, 2009 This thesis deals with a pattern classification problem, which geometrically implies data separation in some Euclidean feature space. The task is to infer a classifier (a separating surface) from a set or sequence of observations.
Kharechko, Andriy
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source