Results 91 to 100 of about 476,732 (307)
Urban Commercial Space Vitality Evaluation Method Based on Social Media Data: The Case of Shanghai
LandSocial media has rapidly intervened in the interaction between urban consumers and commercial space, further reshaping the structure of urban commercial space.
Yuwen Zhang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Spatial and Temporal Patterns in the Cod Fisheries of the North Atlantic
Conservation & Society, 2015 Atlantic Cod Gadus morhua has been subject to commercial exploitation since the thirteenth century. An analysis of cod fisheries over space and time reveals a pattern of serial depletion that reflects the cross-scale interaction of fish population ...
Anne Hayden +3 more
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Efficiency of Public Goods Provision in Space [PDF]
This article incorporates a political decision process into an urban land use model to predict the likely location of a public good. It fills an important gap in the literature by modeling the endogenous location of open space.
Travis Warziniack
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Jurnal Pembangunan Wilayah dan Kota, 2017 Kapas Subdistrict as an oil and gas area of Sukowati Field in Tuban Block with domination of oil and gas mining sector has amount 86,62%, have changed the economic structure and livelihoods tend to tertiary sector.
Dwi Ratna Putri Purnamaningsih
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Formation and large-scale patterns of filament channels and filaments
, 2014 2015ASSL..415..355MThe properties and large-scale patterns of filament channels and filaments are considered. Initially, the global formation locations of filament channels and filaments are discussed, along with their hemispheric pattern.
Duncan H. Mackay, Mackay, Duncan Hendry
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Re-examining urban region and inferring regional function based on spatial–temporal interaction
International Journal of Digital Earth, 2019 Urban system is shaped by the interactions between different regions and regions planned by the government, then reshaped by human activities and residents’ needs. Understanding the changes of regional structure and dynamics of city function based on the
Haiyan Tao +3 more
doaj +1 more source