Results 51 to 60 of about 6,320,743 (323)
Epigenetics & ChromatinBackground Histone Post-Translational Modifications (PTMs) are important epigenetic marks, whose specific pattern over the chromatin plays a critical role in turning the corresponding gene on/off. During DNA replication in mitotic cells, the histone PTMs
B. N. Balakrishna Prabhu +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
GANFIT: Generative Adversarial Network Fitting for High Fidelity 3D Face Reconstruction [PDF]
Computer Vision and Pattern Recognition, 2019 In the past few years, a lot of work has been done towards reconstructing the 3D facial structure from single images by capitalizing on the power of Deep Convolutional Neural Networks (DCNNs).
Baris Gecer +3 more
semanticscholar +1 more source
Increased spatial randomness and disorder of nucleates in dark-phase electrodeposition lead to increased spatial order and pattern fidelity in phototropically grown Se–Te electrodeposits [PDF]
, 2020 The role of nucleation was investigated during phototropic growth of Se–Te. Under low levels of mass deposition (mass equivalent of −3.75 mC cm⁻² of charge passed) that produced small nucleate spacings, patterns in photoelectrochemically deposited Se–Te ...
Van Muñoz, Lorenzo X. +2 more
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Low-fidelity feather pattern in flightless birds.
, 2019 (A) Visualisation of feather primordia (CTNNB1 gene expression) during and after dorsal patterning in flighted (chicken and duck) and nonflighted (ostrich and emu) birds.
Kevin J. Painter (227547) +18 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
MicromachinesInverse lithography technology (ILT) plays a pivotal role in advanced semiconductor manufacturing because it enables pixel-level mask modifications, significantly enhances pattern fidelity, and expands process windows. However, traditional gradient-based
Jie Zhou +5 more
doaj +1 more source
Sensors, 2019 Design of antennas for the Internet of Things (IoT) applications requires taking into account several performance figures, both electrical (e.g., impedance matching) and field (gain, radiation pattern), but also physical constraints, primarily concerning
Slawomir Koziel +1 more
doaj +1 more source
Controlling cell shape on hydrogels using lift-off protein patterning. [PDF]
PLoS ONE, 2018 Polyacrylamide gels functionalized with extracellular matrix proteins are commonly used as cell culture platforms to evaluate the combined effects of extracellular matrix composition, cell geometry and substrate rigidity on cell physiology.
Jens Moeller +5 more
doaj +1 more source