Results 61 to 70 of about 133,577 (291)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Durable, Cost-Effective Pavement Markings Phase I: Synthesis of Current Research, June 2001 [PDF]

, 2001
Pavement marking technology is a continually evolving subject. There are numerous types of materials used in the field today, including (but not limited to) paint, epoxy, tape, and thermoplastic.

core  

Standardized Testing of Non-Standard Photovoltaic Pavement Surfaces [PDF]

, 2016
Emerging photovoltaic products have expanded the applications for the technologies into markets previously unconsidered for what was thought to be a delicate electronic product.
Coutu, Ronald A., Jr., Lake, Robert A., Nussbaum, John H.   +2 more
core   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Effects of existing concrete pavement condition on performance of unbonded jointed plain concrete overlay

Journal of Traffic and Transportation Engineering (English ed. Online), 2019
Unbonded concrete overlay (UBCO) is the most used pavement rehabilitation technique across United States with an overall usage of 47% amongst all the rehabilitation methods. It is aimed to improve the performance of any deteriorated/cracked jointed plain
Gauhar Sabih, Rafiqul A. Tarefder
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Evaluation of the pavement performance

Bulletin of the Polish Academy of Sciences Technical Sciences, 2015
Abstract This paper focuses on evaluation of two laboratory-based methods of compaction of foamed bitumen and bitumen emulsion mixes: impact compaction with a Marshall hammer and static compaction using a hydraulic press. The investigated compaction methods were assessed in terms of their impact on the physical and mechanical properties of produced
M. Iwański, A. Chomicz-Kowalska
openaire   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

PERFORMANCE ENHANCEMENT OF ASPHALT PAVEMENT [PDF]

Al-Azhar Bulletin of Science- Basic Science Sector, 2013
Age hardening of paving grade asphalt is a major factor affecting the durability of bitumen pavement. In this research, 60/70 penetration grade asphalt is modified using Styrene Butadiene Rubber(SBR) in percentages by weight of asphalt ranging from 2 to 6% and 1% by weight of asphalt of an antioxidant namely 4.4.
openaire   +1 more source