Results 31 to 40 of about 66,288 (247)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Effect of Ultrasound Combined with Plasma-Activated Water on Lethal and Sublethal Injury Against Escherichia coli

Foods
Plasma-activated water (PAW) treatment is a promising technique for food processing, but it causes sublethal injury (SI) to microorganisms. This study investigated the effect of ultrasound (US) combined with PAW (US-PAW) on SI of Escherichia coli (E ...
Xin Wen, Meimei Nie, Zhongyuan Zhang, Lingming Xiong, Jialin Feng, Zhi Zhang, Dajing Li, Yihong Bao, Haihong Wu   +8 more
doaj   +1 more source

Effects of Astaxanthin from Litopenaeus Vannamei on Carrageenan-Induced Edema and Pain Behavior in Mice

Molecules, 2016
Carrageenan produces both inflammation and pain when injected in mouse paws via enhancement of reactive oxygen species formation. We have investigated an effect of astaxanthin extracted from Litopenaeus vannamei in carrageenan-induced mice paw edema and ...
Zulkiflee Kuedo, Anantita Sangsuriyawong, Wanwimol Klaypradit, Varomyalin Tipmanee, Pennapa Chonpathompikunlert   +4 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Enhancing germination and seedling growth of barley using plasma-activated water (PAW) with neutralized pH

Cogent Food & Agriculture
Achieving the highest seed germination and seedling growth rates is of paramount importance to maximize overall crop productivity. Among different technologies aiming at increasing seed germination and early plant growth, cold atmospheric pressure plasma
Mahmoud F. Seleiman, Nawab Ali, Emmanuely Z. Nungula, Harun I. Gitari, Bushra A. Alhammad, Martin L. Battaglia   +5 more
doaj   +1 more source

Behavioral Study of Parkinson's Disease Rats Model with DigiGait^TM Imaging System

康复学报, 2022
ObjectiveTo detect the feasibility of DigiGaitTM Imaging System in evaluating gait changes in rats model with Parkinson's disease (PD).MethodsA total of 24 clean male SD rats were randomly divided into normal group, sham operation group and model group ...
LIU Xinhao, MA Shujie, DING Daofang, LUO Kailiang, MA Xinran, JIANG Wenling, HU Jun   +6 more
doaj  

Combined Lycium barbarum Polysaccharides with Plasmon-Activated Water Affect IFN-γ/TNF-α Induced Inflammation in Caco-2 Cells

Pharmaceuticals, 2023
The effects of Lycium barbarum polysaccharides (LBP) and plasmon-activated water (PAW) against IFN-γ/TNF-α induced inflammation in human colon Caco-2 cells were investigated.
Yu Zhi Lian, Yu-Chuan Liu, Chun-Chao Chang, Tomonori Nochi, Jane C.-J. Chao   +4 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Kahweol, a natural diterpene from coffee, induces peripheral antinociception by endocannabinoid system activation

Brazilian Journal of Medical and Biological Research, 2021
Kahweol is a compound derived from coffee with reported antinociceptive effects. Based on the few reports that exist in the literature regarding the mechanisms involved in kahweol-induced peripheral antinociceptive action, this study proposed to ...
L.S. Guzzo, C.C. Oliveira, R.C.M. Ferreira, D.P.D. Machado, M.G.M. Castor, A.C. Perez, F. Piscitelli, V. Di Marzo, T.R.L. Romero, I.D.G. Duarte   +9 more
doaj   +1 more source