TRPV2 in muscle satellite cells is crucial for skeletal muscle remodelling. [PDF]
Chen Y +8 more
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Single-Cell RNA-Sequencing Reveals Cachectic Satellite Cell Population in Muscle of Male Mice With Cancer Cachexia. [PDF]
Brown A +5 more
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Biallelic PAX7 variants cause a novel Satellite Cell-opathy with progressive muscle involvement resembling facioscapulohumeral muscular dystrophy. [PDF]
Ganassi M +18 more
europepmc +1 more source
Divergent stem cell mechanisms govern the primary body axis and appendage regeneration in the axolotl. [PDF]
Wang L +17 more
europepmc +1 more source
Pathological changes and therapeutic strategies for sarcopenia. [PDF]
Yang K +5 more
europepmc +1 more source
Regenerative Medicine: Advanced Therapy for Muscle Tissue Restoration. [PDF]
Deev R +5 more
europepmc +1 more source
Nuclear entry of AS160 as a transcriptional regulator of satellite cells for muscle regeneration. [PDF]
Yang X +15 more
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Biallelic variants in the transcription factor PAX7 are a new genetic cause of myopathy
Genetics in Medicine, 2019Skeletal muscle growth and regeneration rely on muscle stem cells, called satellite cells. Specific transcription factors, particularly PAX7, are key regulators of the function of these cells. Knockout of this factor in mice leads to poor postnatal survival; however, the consequences of a lack of PAX7 in humans have not been established.Here, we study ...
Tobias Haack +2 more
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The developmental paired-type gene Pax7 is expressed in skeletal muscle and brain during development and in the adult mouse. In this study, RNA was isolated from the brains and skeletal muscles of the limbs of adult BALB/c and SJL/J mice to determine whether there were alternate transcripts which could account for the biological diversity of Pax7. Four
M R, Ziman, P H, Kay
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