Results 51 to 60 of about 6,337 (198)
Projected COVID-19 Mortality Reduction From Paxlovid Rollout
JAMA Health Forum, 2023 This decision analytical model study assesses projections of simulated effects of Paxlovid rollout on hospitalizations and mortality using 10 models.
Khunte, Mihir +3 more
openaire +2 more sources
A case report of severe hyponatremia secondary to Paxlovid‐induced SIADH
Clinical Case Reports, 2023 Key Clinical Message Nirmatrelvir‐ritonavir (Paxlovid) is a brand‐new oral antiviral medication for treating mild to severe COVID‐19. The Food and Drug Administration (FDA) issued an Emergency Use Authorization (EUA) for ritonavir‐nirmatrelvir on ...
Sarah Mohamed +7 more
doaj +1 more source
Situation Analysis of Pharmacovigilance to Medicines in the Western Pacific Region [PDF]
, 2023 聖路加国際大学修士(公衆衛生学 ...
Hitomi, Kubota, 久保田, 瞳
core
Intrinsic and Relative Valuation of Pfizer Inc. [PDF]
, 2023 The aim of the thesis was to estimate the intrinsic and relative value of Pfizer Inc. by analysing both: Pfizer and the pharmaceutical industry. To create a multitude of valuation estimates the following valuation methods were utilized: Discounted Cash ...
Garshol, Eirik, Thornes, Johannes
core +3 more sources
COVID-19: Variants, Immunity, and Therapeutics for Non-Hospitalized Patients [PDF]
, 2023 The continuing transmission of coronavirus disease 2019 (COVID-19) remains a world-wide 21st-century public health emergency of concern. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused greater than 600 million cases of COVID-19 ...
Lee, Cameron, Lee|, suzuki, jon, Suzuki|
core +1 more source
VIEW, EarlyView.This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu +10 more
wiley +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 5, Page 1026-1036, April 2026.ABSTRACT Objective Indigenous pregnant and postpartum people are more likely to experience severe maternal morbidity (SMM) and mortality than non‐Indigenous groups. We sought to explore how community and societal factors, culture, and resilience impact Native American individuals' pregnancy experiences and might offer insights to address inequities in ...
Jennifer L. Murray +8 more
wiley +1 more source
International Journal of Infectious DiseasesIntroduction: COVID-19 poses a severe threat to high-risk populations, such as the elderly and those with incomplete vaccination. Despite the availability of treatments like Paxlovid and Molnupiravir, their relative effectiveness in preventing severe ...
Dr Yi-hsuan Chen +4 more
doaj +1 more source
Antivirals for the treatment of mild and moderate COVID-19 in South Africa [PDF]
, 2023 While the majority of COVID‐19 cases in South Africa (SA) are mild, patients with severe COVID‐19 requiring hospitalisation present with significant morbidity and mortality and place a substantial burden on healthcare services.
Gengiah, T N +3 more
core +2 more sources
Microbial Biotechnology, Volume 19, Issue 4, April 2026.The target sites of COVID‐19 antivirals discussed in the present opinion paper, namely the RNA dependent RNA polymerase Nsp12 and of the main viral protease Nsp5, are indicated by a red star in the overview of the replication cycle of coronavirus SARS‐CoV‐2.
Harald Brüssow
wiley +1 more source