Results 171 to 180 of about 856,328 (294)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Azimuthal anisotropy in Pb+Pb, Xe+Xe and p+Pb collisions and vn–pt correlations in Pb+Pb and p+Pb collisions with the ATLAS experiment [PDF]
Proceedings of European Physical Society Conference on High Energy Physics — PoS(EPS-HEP2019), 2020 openaire +1 more source
Uranium-Lead dating of hominid fossil sites in South Africa [PDF]
, 2005 Discoveries of hominid, or apeman, fossils in the twentieth century have brought human evolution into the scientific spotlight. It is important that ages are assigned to such hominids so that their place in human evolution can be established.
Walker, Joanne
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Timing of deposition, orogenesis and glaciation within the Dalradian rocks of Scotland: constraints from U-Pb zircon ages [PDF]
, 2002 The stratigraphical and structural continuity of the Late Proterozoic Dalradian rocks of the Scottish Highlands is re-examined in the light of new U-Pb zircon ages on the tuffs belonging to the Tayvallich Volcanic Formation (601 ñ 4 Ma), and on the late ...
Paterson, BA +15 more
core
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Large piezoelectric effect in Pb-free ceramics.
Physical Review Letters, 2009 Wenfeng Liu, X. Ren
semanticscholar +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Az Pb(II) kölcsönhatásának vizsgálata maltollal és piridinonnal
, 2014 Az Pb(II) kölcsönhatásának vizsgálata maltollal és piridinonnal, pH-potenciometriásan, NMR-rel és ESI-MS-sel.gjkémiaBSc ...
Nagy, Imre
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source