Results 191 to 200 of about 849,713 (290)

Fire at the boundary: Airborne toxic metals from the 2025 Los Angeles urban firestorm. [PDF]

Sci Adv
Baliaka HD, Ward RX, Raffuse SM, Ries B, Cui Y, Wu D, Liu R, Barut C, Hasheminassab S, Tissot FLH, Russell AG, Seinfeld JH, Flagan RC, Bahreini R, Wennberg PO, Ng NL.   +15 more
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Longitudinal associations between childhood maltreatment and suicidal ideation in youth: the roles of complex posttraumatic stress disorder symptoms and interpersonal factors. [PDF]

Front Psychiatry
Yu Q, Li Y, Wang L, Guo J, Wang W.
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Characteristics of Pb I, Pb II, Pb III, and Pb IV Lines Revealed in the Instantaneous Spectrograms

Proceedings of the Imperial Academy, 1935
NAGAOKA, Hantaro, FUTAGAMI, Tetsugoro
openaire   +2 more sources

Banding Karyotyping From Peripheral Blood Is a Useful Method for the Diagnostic Workup of Myelodysplastic Neoplasia and CMML. [PDF]

Genes Chromosomes Cancer
Heusler C, Hildebrandt B, Schulz F, Nachtkamp K, Strupp C, Flatten V, Dietrich S, Gattermann N, Germing U.   +8 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Enhanced but not superior: Performance outcomes from the inaugural enhanced games. [PDF]

Physiol Rep
Azevedo RA, Coutinho LF, Gonçalves MC, Oliveira HA, Gonçalves GJ, Campos M, Roschel H, Gualano B.   +7 more
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source