Results 61 to 70 of about 154,598 (309)

Mosquito saliva decreases cytokine production in human PBMCs.

, 2018
Human PBMCs from two donors were stimulated with either mosquito saliva or untreated media. Supernatant cytokine concentrations were assessed daily via multiplex cytokine bead array assay.
Megan B. Vogt (495751), Silke Paust (5234249), Jennifer L. Spencer Clinton (5234252), Rebecca Rico-Hesse (3130833), Anismrita Lahon (3130839), Ravi P. Arya (240556), Alexander R. Kneubehl (3130842)   +6 more
core   +1 more source

Human PBMCs Form Lipid Droplets in Response to Spike Proteins

, 2023
Intracellular lipid droplets (LDs) can accumulate in response to inflammation, metabolic stresses, and other physiological/pathological processes.
Julia Held, Metayer, Charles, Wurm, Maria J., Held, Julia, Raussin, Guillaume, Welte, Tobias, Paco Pino, Maria J. Wurm, Florian M. Wurm, Sivaraman, Kokilavani, Olejnicka, Beata, Stephanie Anchisi, Kokilavani Sivaraman, Tobias Welte, Janciauskiene, Sabina, Wurm, Florian M., Guillaume Raussin, Pino, Paco, Nicolas Dagany, Sabina Janciauskiene, Wrenger, Sabine, Sabine Wrenger, Charles Metayer, Anchisi, Stephanie, Dagany, Nicolas, Beata Olejnicka   +25 more
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Transcriptional Landscape of Enhancer RNAs in Peripheral Blood Mononuclear Cells from Patients with Systemic Lupus Erythematosus

Journal of Inflammation Research, 2022
Gangqiang Guo,1,* Huijing Wang,2,* Xinya Tong,1,* Lele Ye,1 Xinyu Shi,1 Su Fang,1 Ya Hu,3 Fei Han,2 Chaosheng Chen,3 Ning Ding,1 Bofeng Su,3 Xiangyang Xue,1 Huidi Zhang3 1Wenzhou Collaborative Innovation Center of Gastrointestinal Cancer in ...
Guo G, Wang H, Tong X, Ye L, Shi X, Fang S, Hu Y, Han F, Chen C, Ding N, Su B, Xue X, Zhang H   +12 more
doaj  

Possible association between expression of chemokine receptor-2 (CCR2) and amyotrophic lateral sclerosis (ALS) patients of North India. [PDF]

PLoS ONE, 2012
BACKGROUND AND OBJECTIVES: We earlier reported elevated chemokine ligand-2 (CCL2) in Indian amyotrophic lateral sclerosis (ALS) patients. We now analysed chemokine receptor-2 (CCR2), the receptor of CCL2, in these ALS patients.
Pawan K Gupta, Sudesh Prabhakar, Neel K Sharma, Akshay Anand   +3 more
doaj   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Relationships Between Vitamin D Status and Cytokine: Results from Interferon-Based Therapy in Non-Cirrhotic, Treatment-Naïve Patients with Chronic Hepatitis C Infection

Journal of Inflammation Research, 2020
Hsuan-Wei Chen,1 Yi-Lin Chiu,2 Tsai-Yuan Hsieh,1 Peng-Jen Chen,1 Tien-Yu Huang,1 Hsuan-Hwai Lin,1 Yu-Lueng Shih,1 Jung-Chun Lin1 1Division of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center,
Chen HW, Chiu YL, Hsieh TY, Chen PJ, Huang TY, Lin HH, Shih YL, Lin JC   +7 more
doaj  

Annexin V staining of PBMCs.

, 2014
PBMCs were left unstimulated or treated with iron-catechol alone or with PMA alone or in the presence of apo- or holo-Bos d 5. Living cells were gated on forward and side scatter and then plotted for CD4 and Annexin V.
Erika Jensen-Jarolim (203031), Araceli Diaz-Perales (5660143), Franziska Roth-Walter (614108), Luis F. Pacios (614109), Josef Singer (614111), Gerlinde Hofstetter (352009), Cristina Gomez-Casado (287523), Georg A. Roth (614110)   +7 more
core   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

CITE-seq for PBMCs v1

, 2020
This is a protocol for CITE-seq for PBMCs. It includes the steps for Thawing samples and Antibody Staining.
Nicola Wilson, Fernando Calero-Nieto, Javier Rodríguez-Ubreva, Bertie Gottgens, Esteban Ballestar, Roser Vento-Tormo   +5 more
openaire   +1 more source