Results 71 to 80 of about 154,598 (309)

Effect of TCERG1 on apoptosis using PBMCs.

, 2015
(A) Transiently reduced expression of TCERG1 in PBMCs decreases apoptosis induced by staurosporine. Apoptosis induced by staurosporine was measured by flow cytometry in EYFP+ PBMCs transiently transfected with pGeneClip-shTCERG1-(1-3-4) or control ...
Carlos Suñé (812755), Mayte Coiras (79439), Marta Montes (812749), José Alcamí (79441), Elena Mateos (812752), Cristina Moreno-Castro (812751), Jara Majuelos (812753), Cristina Hernández-Munain (812754), F. Javier Oliver (35545), Soraya Becerra (812750)   +9 more
core   +1 more source

ELISPOT responses in PBMCs before ART discontinuation.

, 2022
Gag-, Env-, and Pol-specific IFNγ responses are shown for each animal at week -7/-8, week 0, week 8 and week 32 as spot-forming cells (SFCs) per million PBMCs. Red lines indicate median values. (TIFF)
Brian Moldt (313901), Heather Stephenson (12447041), Craig S. Pace (12447047), Mark Nagel (12447044), Romas Geleziunas (549808), Brian Carr (1801810), Erica N. Borducchi (12447035), Magdeleine Hung (158371), Abishek Chandrashekar (11028092), Dan H. Barouch (8129832), Joseph P. Nkolola (12447038), Nathan D. Thomsen (12447050), Joshua Goldsmith (599043), Wade S. Blair (235574)   +13 more
core   +1 more source

High‐Throughput Digital Decoding of Vascular Heterogeneity in Patient‐Specific Tumor Microenvironments

Advanced Healthcare Materials, EarlyView.
ABSTRACT Quantitative characterization of vascular heterogeneity in complex microphysiological systems (MPS), particularly within patient‐derived tumor microenvironments, remains a major challenge for scalable disease modeling and therapeutic evaluation.
Jungseub Lee, Wooju Park, Sujin Hyung, Sangmin Jung, Kyungho Lee, Junseok Jeon, Noo Li Jeon, Jeeyun Lee, Hye Ryoun Jang, Jihoon Ko   +9 more
wiley   +1 more source

Comparison of Epstein–Barr virus and Kaposi’s sarcoma-associated herpesvirus viral load in peripheral blood mononuclear cells and oral fluids of HIV-negative individuals aged 3–89 years from Uganda

Infectious Agents and Cancer, 2023
We previously found that age, sex and malaria were associated with KSHV in individuals from Uganda. In this study, we have evaluated these same factors in relation to EBV in the same specimens.
Angela Nalwoga, Vickie Marshall, Wendell Miley, Nazzarena Labo, Denise Whitby, Robert Newton, Rosemary Rochford   +6 more
doaj   +1 more source

A Reproducible and Scalable Process for High Yield Mesenchymal Stromal Cell Extracellular Vesicles Production

Advanced Materials Technologies, EarlyView.
Mesenchymal stem cell derived extracellular vesicles (MSC‐EVs) are a promising therapeutic tool for regenerative medicine. However, the field lacks a reproducible high‐yield production method to answer the quantities needed for clinical translation.
Christophe Wong, Elise Madec, Jeanne Volatron, Max Piffoux, Amanda K. A. Silva, Florence Gazeau, Jean‐Philippe Herbeuval, Thibaut Fourniols   +7 more
wiley   +1 more source

Chicken Peripheral Blood Mononuclear Cells Response to Avian Leukosis Virus Subgroup J Infection Assessed by Single-Cell RNA Sequencing

Frontiers in Microbiology, 2022
Chicken peripheral blood mononuclear cells (PBMCs) exhibit wide-ranging cell types, but current understanding of their subclasses, immune cell classification, and function is limited and incomplete. Here we performed single-cell RNA sequencing (scRNA-seq)
Xiaoyun Qu, Xiaobo Li, Ziwei Li, Ming Liao, Manman Dai   +4 more
doaj   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Purification of PBMCs v1

, 2020
This protocol details the steps and methods of PBMC purification
openaire   +1 more source

Statistics on the horse PBMCs transcriptome assembly.

, 2015
Statistics on the horse PBMCs transcriptome assembly.
Eliane Marti (157764), Eman Hamza (705680), Simone Lanz (705843), Michaela Drögemüller (220341), Vidhya Jagannathan (13914), Alicja Pacholewska (705841), Emmanouil T. Dermitzakis (120302), Vincent Gerber (171558), Jolanta Klukowska-Rötzler (705842), Tosso Leeb (81674)   +9 more
core   +1 more source

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

Advanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu, Guanqun Li, Dongxu Lu, Haoran Ding, Tianqi Lu, Yuhang Sui, Can Zhang, Yu Xie, Rui Kong, Hua Chen, Xuewei Bai, Hongtao Tan, Dongbo Xue, Xianzhi Meng, Le Li, Bei Sun   +15 more
wiley   +1 more source