Gram-negative metallo-β-lactamase-producing bacteria can be extremely problematic, especially when found to be extensively drug-resistant (XDR). Cefiderocol is a novel antimicrobial that has been shown to overcome most carbapenemases, with very rare ...
Kevin R. Barker +5 more
doaj +1 more source
Novel PBP3 insertions in MDR Escherichia coli from blood stream infections: A threat for newer β-Lactam combinations [PDF]
Naveen Kumar Devanga Ragupathi +3 more
openalex +1 more source
Long range transcriptional control of virulence critical genes in Mycobacterium tuberculosis by nucleoid-associated proteins? [PDF]
Buxton, R. S. +5 more
core +1 more source
Functional characterisation of the activities and interactions of Gram-negative penicillin-binding proteins PBP1b and PBP3 [PDF]
The clinical introduction of antibiotics revolutionised medicine, however the emergence of resistant bacteria is threatening their use. Of particular worry are multi-drug resistant Gram-negative bacteria that have evaded the development of any new treatment classes since the 1960’s, making them particularly difficult to treat.
openaire
Molecular Insights into the β‑Lactam α‑Methyl Modulation of <i>Pseudomonas aeruginosa</i> Penicillin-Binding Protein 3 (PBP3): Loop Dynamics and Hydration Network Modulation. [PDF]
Reyes DV, Nellas RB.
europepmc +1 more source
Sulbactam-Durlobactam for Carbapenem-Resistant <i>Acinetobacter baumannii-calcoaceticus</i> Complex. [PDF]
Nappi F.
europepmc +1 more source
Escherichia coli strains possessing a four amino acid YRIN insertion in PBP3 identified as part of the SIDERO-WT-2014 surveillance study [PDF]
Takafumi Sato +8 more
openalex +1 more source

