Results 201 to 210 of about 16,022 (277)

Effect of PCBs on the lactational transfer of methyl mercury in mice: PBPK modeling

, 2008
Sun Ku Lee, Dwayne Hamer, Cathy L. Bedwell, Manupat Lohitnavy, Raymond S. H. Yang   +4 more
openalex   +2 more sources

Role of metabolites in drug-drug interactions. [PDF]

Drug Metab Pharmacokinet
Isoherranen N.
europepmc   +1 more source

Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women [PDF]

Jia Ning, Amita Pansari, Karen Rowland Yeo, Aki T. Heikkinen, Catriona Waitt, Lisa M. Almond   +5 more
openalex   +1 more source

Optimization of Bottom-Up PBPK Model Development in SIMCYP via Retrospective Analysis of Clinical Human PK Data. [PDF]

Clin Transl Sci
Schulz Pauly JA, Leblanc AF, Chowdhury EA, Qian Y, Rezaei L, Lee CM, Badawi M, Kikuchi R.   +7 more
europepmc   +1 more source

Capillary Permeability Model을 반영한 Whole-body PBPK Model의 구축에 관한 연구

, 2015
정유성
openalex   +1 more source

Progress of coproporphyrin as an endogenous biomarker for transporter-mediated drug-drug interactions. [PDF]

Front Pharmacol
Zhao P, Hu Y, Hu X, Xu Y, Jiang B, Lou H.   +5 more
europepmc   +1 more source

Machine learning to predict food effects during drug development: a comprehensive review. [PDF]

J Cheminform
Shah A, Bi F, Yang J.
europepmc   +1 more source

Physiologically-based pharmacokinetic modeling and simulation for initial dose optimization of levetiracetam in pediatrics. [PDF]

Front Pharmacol
Macente J, Hernandes Bonan R, Caleffi-Marchesini ER, Leira Pereira LR, De Freitas Lima P, Annaert P, Allegaert K, Diniz A.   +7 more
europepmc   +1 more source

Pharmacokinetic and Pharmacodynamic Modeling of Antibody-Drug Conjugates. [PDF]

Cancers (Basel)
Glassman PM.
europepmc   +1 more source

Opportunities for machine learning and artificial intelligence in physiologically-based pharmacokinetic (PBPK) modeling. [PDF]

Adv Drug Deliv Rev
Talkington AM, Cao Y, Kearsley AJ, Lai SK.   +3 more
europepmc   +1 more source