Results 181 to 190 of about 9,895 (222)

Virtual Bioequivalence Assessment of Long-Acting Injectable Suspensions Using PBPK Modeling: Part 2. Type I Error and Safe Space Analyses. [PDF]

AAPS J
Morris NM, Jamei M, Alam K, Tsakalozou E, Donnelly M, Feng K, Bois FY.   +6 more
europepmc   +1 more source

From Population-Based PBPK to Individualized Virtual Twins: Clinical Validation and Applications in Medicine. [PDF]

J Clin Med
Gonçalves M, Barata P, Vale N.
europepmc   +1 more source

Predicting Pharmacokinetic Variability and Drug Interaction Risk Using Omics-Based Biomarkers. [PDF]

Clin Transl Sci
Prasad B.
europepmc   +1 more source

Dose optimization of inhaled tigecycline in humans to overcome inherent adverse events and maximize bacterial clearance using a physiologically-based pharmacokinetic modeling approach. [PDF]

Front Tuberc
Park H, Singh A, Srivastava A, Thalluri B, Mathieu CJ, Gupta P, Pearce CM, Zohaib Ali M, Alshiraihi IM, Maloney Norcross SE, Hickey AJ, Gonzalez-Juarrero M, Meibohm B.   +12 more
europepmc   +1 more source

Utility of a physiologically-based pharmacokinetic model for investigating time-dependent variability in the fetal-to-maternal plasma concentration ratio of digoxin. [PDF]

J Pharmacokinet Pharmacodyn
Okuba K, Ikeda K.
europepmc   +1 more source

Comprehensive Pathophysiology Repository for PBPK Modeling in Liver Cirrhosis: Quantifying Continuous Disease Progression and Population Variability. [PDF]

CPT Pharmacometrics Syst Pharmacol
Schneider ARP, Baier V, Schlender JF, Kuepfer L.   +3 more
europepmc   +1 more source

Assessing transporter-mediated rifampin-linezolid interaction using physiologically-based pharmacokinetic modelling. [PDF]

Br J Clin Pharmacol
Nguyen HD, Pham VH, Hoglund RM, Tarning J, Ding J.   +4 more
europepmc   +1 more source

Physiologically-Based Pharmacokinetics of Ribociclib Drug-Drug Interactions and Organ Impairment Pharmacokinetics in Early Breast Cancer. [PDF]

Pharmaceuticals (Basel)
Ji Y, Huth F, Wang C, Schiller H, Combes FP, Crown J, Fasching PA, Zarate JP, Untch M.   +8 more
europepmc   +1 more source

Quantitative systems toxicology approach that integrates PBPK and core hepatic metabolism: a case study with valproic acid. [PDF]

Front Pharmacol
Gupta V, Jo H, Fisher CP, Kierzek AM.
europepmc   +1 more source

PBPK in liver cirrhosis population

, 2019
openaire   +1 more source