Results 161 to 170 of about 11,787 (237)

A PBPK model for benzo(A)pyrene in the rat

European Journal of Pharmaceutical Sciences, 1996
D. Moir, A. Viau, I. Chu, F.C.P. Law, K. Krishnan   +4 more
openaire   +1 more source

Understanding Postmarketing Requirements and Commitments for CYP3A-Mediated Drug-Drug Interactions: An Analysis of FDA-Approved Drugs From 2015 to 2024. [PDF]

Clin Transl Sci
Yu J, Petrie I, Argon S, Owens K, Ragueneau-Majlessi I.   +4 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic (PBPK) Modeling of Antidepressants: A Scoping Review of Existing Models, Applications, and Software Tools. [PDF]

Clin Pharmacokinet
Huber RL, Scherf-Clavel O.
europepmc   +1 more source

The value of target-site physiologically-based pharmacokinetics for high-affinity small molecules: a mechanistic foundation for precision dosing in oncology and hematology. [PDF]

Cancer Chemother Pharmacol
van der Gaag S, Oprea-Lager DE, Vis AN, Hendrikse H, Bartelink IH.   +4 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling for Mechanistic Analysis of Food Effects: A Case Study with Radotinib. [PDF]

Pharm Res
Kang M, Kim NY, Shin JS, Park MS, Hong E, Lee JI.   +5 more
europepmc   +1 more source

Development of a Disease-Specific Virtual Malaria Population for Physiologically-Based Pharmacokinetic Modeling. [PDF]

CPT Pharmacometrics Syst Pharmacol
Ding J, Pei Q, Hoglund RM, Tarning J.
europepmc   +1 more source

Physiologically Based Pharmacokinetic (PBPK) Modeling of FIX in Pediatric Hemophilia B: Extravascular Distribution and Dosing Optimization. [PDF]

Pharmaceutics
Liu M, Liu G, Ling Q, Chen Y, Xu H, Wu R, Chen Z, Zhao L.   +7 more
europepmc   +1 more source

Narrow Therapeutic Index Drugs: Regulatory Frameworks, Bioequivalence, and Model-Informed Precision Dosing. [PDF]

Pharmaceutics
Liu M, Wang Z, Chen Y, Jia Y, Xu L, Xu H, Li J, Zhao L.   +7 more
europepmc   +1 more source

PBPK Modeling of Esomeprazole to Support Adolescent Pharmacokinetic Extrapolation and Label Extension in Chinese Patients With Gastroesophageal Reflux Disease (GERD). [PDF]

J Clin Pharmacol
Jin Y, Ding J, Hua X, Duan W, Chen M, Zhou Z, Pandherpur RV, Dong J, Pradeep S, Ma P, Tang W, Zhou D.   +11 more
europepmc   +1 more source

Artificial Intelligence in the Design and Development of Nanoparticle Drug Delivery Systems: A Systematic Review. [PDF]

Adv Pharmacol Pharm Sci
Haddad R.
europepmc   +1 more source