Results 161 to 170 of about 9,895 (222)

Guiding a Diclofenac Sodium Dual-Release Sustained Formulation Development Through In Vitro-In Vivo Relationship Based on Physiologically Based Pharmacokinetics. [PDF]

Pharmaceutics
Wang Q, Guo P, Hu T, Li L, Zhu T, Pan Y, Xiang X, Wang J.   +7 more
europepmc   +1 more source

Virtual Bioequivalence Assessment of Long-acting Injectable Suspensions Using PBPK Modeling: Part 1. Impact of particle Size on Formulation Variability. [PDF]

AAPS J
Morris NM, Djehizian A, Mittapelly N, Telaprolu KC, Holland BW, McNally K, Polak S, Jamei M, Alam K, Tsakalozou E, Donnelly M, Feng K, Bois FY.   +12 more
europepmc   +1 more source

Machine Learning Meets Pharmacokinetics: A Comparative Analysis of Predictive Models for Plasma Concentration-Time Profiles. [PDF]

CPT Pharmacometrics Syst Pharmacol
Jost F, Giegerich C, Grebner C, Matter H, Cordes H.   +4 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling and Therapeutic Drug Monitoring for Ertapenem Dose Optimization in Hypoalbuminemia Elderly Patients. [PDF]

Drug Des Devel Ther
Du X, Dong Z, Li Y, Wu Y, Wu H.
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling to Assess Antiretroviral-BTK Inhibitor Interactions and Provide Recommendations for Co-Administration Regimens. [PDF]

Pharmaceutics
Chen L, Wang X, Li L, Yang Y, Liu Y, Chen W.   +5 more
europepmc   +1 more source

Translational Modeling of Gut Microbiome-Mediated Drug Metabolism: A Case Example of Sulfasalazine. [PDF]

CPT Pharmacometrics Syst Pharmacol
Cheng L, Cai J, Auster A, Cho S, Keir M, Rhee H, Kapili B, Shalon D, Ning M.   +8 more
europepmc   +1 more source

RENAsym, a quantitative systems toxicology platform model, designed to predict drug-induced kidney injury indicates polymyxin B and valproate overdose toxicity potential while simultaneously demonstrating acetaminophen and valproate safety at therapeutic levels. [PDF]

Toxicol Sci
Vallejo C, Bhargava P, Hamzavi N, McDaniel M, Lakhani VV, Qi T, Battista C, Clemens L, Shoda LKM, Kenz ZR, Tallapaka S, Gebremichael Y, Woodhead JL.   +12 more
europepmc   +1 more source

Mechanistic Physiologically Based Pharmacokinetic Modeling to Predict CYP3A4-Mediated Drug-Drug Interactions of Flumatinib as Both a Victim and a Perpetrator. [PDF]

Drug Des Devel Ther
Alifu M, Chu X, Zhu X, Mak WY, Zheng A, Pan C, He Q, Zhu X, Kuai Z, Xiang X.   +9 more
europepmc   +1 more source

Biomonitoring of bisphenol A, S, and F in urine samples from children in Finland. [PDF]

Environ Monit Assess
Poursafa P, Koponen J, Rantakokko P, Helotie I, Koivusalo M.   +4 more
europepmc   +1 more source

An Integrated AIVIVE-PBPK-QIVIVE Framework with HTTK Validation for Probabilistic Risk Assessment of Neodymium Nitrate. [PDF]

Chem Res Toxicol
Wang N, Leng J, Zhang HM, Xu J, Qian KL, Chang XL, Sun NN, Xiao P, Hong XY, Lu DS.   +9 more
europepmc   +1 more source