Results 161 to 170 of about 14,687 (252)

Development of a Pregnancy-Specific Physiologically Based Pharmacokinetics (PBPK) Model for Aspirin. [PDF]

CPT Pharmacometrics Syst Pharmacol
Collins-Smith A, Kammala AK, Phelps MA, Wang XM, Menon R, Costantine MM.   +5 more
europepmc   +1 more source

High-Throughput Physiologically Based Pharmacokinetic Model for Rodent Pharmacokinetics Prediction Using Machine Learning-Predicted Inputs and a Large <i>In Vivo</i> Pharmacokinetics Data Set. [PDF]

Mol Pharm
Bassani D, Andrews-Morger A, Zhang J, Docci L, Cecere G, Pähler A, Belubbi T, Laye P, Shih I, Parrott NJ.   +9 more
europepmc   +1 more source

Leveraging Two-Stage δ Global Sensibility Analysis Method to Inform Parameter Estimation in PBPK Models. [PDF]

Pharm Stat
Cuquerella-Gilabert M, De Carlo A, Sánchez Herrero S, Reig-López J, Merino-Sanjuan M, Tosca EM, Mangas-Sanjuan V, Magni P.   +7 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling in Patients With Hepatic Impairment: Are Changes in Bosutinib Exposure Profiles Driven by Altered Absorption or Distribution? [PDF]

CPT Pharmacometrics Syst Pharmacol
Muto C, Jones HM, Yamazaki S.
europepmc   +1 more source

Sotalol Dose Optimization for Fetal Tachycardia: A Pregnancy Physiologically Based Pharmacokinetic Model Study. [PDF]

Prenat Diagn
van Hove H, van der Heijden JEM, van Uden A, Gijsen VMGJ, Greupink R, de Wildt SN, van Drongelen J.   +6 more
europepmc   +1 more source

Assessment of Vancomycin Penetration into Cerebrospinal Fluid in Patients with Ventriculitis Using a Physiologically Based Pharmacokinetic Approach. [PDF]

Pharm Res
Guimarães LMA, de Vasconcellos Nacif LO, de Lima Benzi JR, de Oliveira Santos MT, Yamada C, Tuon FF, Telles JP, de Lima Moreira F.   +7 more
europepmc   +1 more source

Dose Optimization of Tilmicosin against <i>Pasteurella multocida</i> in Swine by Physiologically Based Pharmacokinetic-Pharmacodynamic Model. [PDF]

J Agric Food Chem
Sun L, Zhang C, Mi K, Wang H, Pan Y, Tao Y, Huang L.   +6 more
europepmc   +1 more source

Applications of Pharmacometrics in Antibody-Drug Conjugate Development. [PDF]

Pharmaceutics
Cheng X, Ji S, Lee Y, Dong H.
europepmc   +1 more source

The pH factor: unraveling drug-drug interactions in protein kinase inhibitors through the regulatory lens. [PDF]

Transl Clin Pharmacol
Stankeviciute S, Tsai A, Rayad N, Kruse M.   +3 more
europepmc   +1 more source

Physiology-Based Pharmacokinetic Modeling for Prediction of Gentamicin Plasma Profile in Dogs with Renal Dysfunction. [PDF]

Pharmaceutics
Martins KSG, Gonzaga LWF, Felix LA, Moraes RS, Okamoto PTCG, Ferrante M.   +5 more
europepmc   +1 more source