Results 141 to 150 of about 14,687 (252)

Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models [PDF]

, 2007
Michaela Vossen, Michael Sevestre, Christoph Niederalt, In-Jin Jang, Stefan Willmann, Andrea N Edginton   +5 more
core   +1 more source

Physiologically-Based Pharmacokinetic Model-Informed Labeling for Cariprazine Drug Interactions With CYP3A Inhibitors. [PDF]

CPT Pharmacometrics Syst Pharmacol
Riad MMH, Marroum P, Shebley M, Xiong H.
europepmc   +1 more source

Human PBPK Modeling

This deliverable will report the final development of the human PBPK models developed within ...
openaire   +1 more source

Subject-Specific Whole-Lung CFPD Coupled with PBPK/PD to Predict Inhaled Bronchodilator Response in Asthmatic and Healthy Subjects. [PDF]

J Aerosol Sci
Rajaraman PK, Zhang X, Comellas AP, Hoffman EA, Lin CL.   +4 more
europepmc   +1 more source

Open Systems Pharmacology Community Conference (OSP-CC) Proceedings 2025. [PDF]

CPT Pharmacometrics Syst Pharmacol
Cordes H, Annaert P, Balazki P, Benamara S, Bonan RH, Butler A, Chenel M, Cui Y, Dallmann A, de Witte WEA, Demeester C, Feick D, Gattacceca F, Geci R, Gerebtzoff G, Gruber A, Guimarães M, Hamadeh A, Hanke N, Ibarra M, Ince I, Kanacher T, Kuepfer L, Mil F, Montaseri G, Nauwelaerts N, Proenca S, Schaller S, Schlender JF, Schneider ARP, Sjögren E, Solodenko J, Staab A, Vrenken P, Troisi C, Teutonico D.   +35 more
europepmc   +1 more source

A PBPK model of Low-concentration Vitamin D Supplementation in the Absence of Sunlight [PDF]

, 2019
Sawyer, Colton
core   +1 more source

Simulation of Imatinib Pharmacokinetics in pregnant women with chronic myeloid leukemia in the third trimester. [PDF]

Eur J Clin Pharmacol
Mian P, Lok CAR, Dontje AEWK, Prins JR, Oude Munnink TH, Nieuwenhuizen L, Gordijn SJ, Touw DJ, Malik P.   +8 more
europepmc   +1 more source

Dose Recommendation of Remimazolam Tosilate for General Anesthesia in Children and Adolescents: Synergistic Combination of PopPK and PBPK Approaches. [PDF]

Pharmaceutics
Liang QY, Hu HH, Djebli N, Huang YY, Jiang H.   +4 more
europepmc   +1 more source

Sorafenib in mice - A Pharmacokinetic study [PDF]

, 2015
Abbiati, ROBERTO ANDREA, Cavallaro, Gennara, Craparo, Emanuela F., Manca, Davide   +3 more
core   +1 more source

Albumin Levels Are Predictive of Cachexia-Induced Time-Dependent Clearance of Therapeutic Antibodies: A Physiologically Based Pharmacokinetic Model of Durvalumab. [PDF]

CPT Pharmacometrics Syst Pharmacol
Proctor JR, Wong H.
europepmc   +1 more source