Results 151 to 160 of about 11,787 (237)

Advances in Machine Learning-Enhanced PBPK Models for Brain-Targeted Drug Delivery via Nanocarriers: A Comprehensive Review. [PDF]

J Funct Biomater
Hu H, Wang Y.
europepmc   +1 more source

Machine Learning Enables Rapid Prediction of Acid-Reducing Agent Drug Interactions: A Streamlined Complement to PBPK Modeling. [PDF]

CPT Pharmacometrics Syst Pharmacol
Qin Y, Yu L, Chen T, Zuo Y, Wang H, Yang G, Pei Q.   +6 more
europepmc   +1 more source

Physiologically based pharmacokinetic modeling to predict human pharmacokinetics of a novel mithramycin analog for Ewing sarcoma. [PDF]

Cancer Chemother Pharmacol
Niloy KK, Horn J, Bhuiyan NH, Bhosale SS, Shaaban KA, Prisinzano TE, Thorson JS, Rohr J, Leggas M.   +8 more
europepmc   +1 more source

Physiologically-based pharmacokinetic model to predict loading dose polymyxin B exposure in critically ill patients with sepsis. [PDF]

Front Pharmacol
Cao Y, Galvidis I, Alimov A, Standing JF, Burkin M, Surovoy Y.   +5 more
europepmc   +1 more source

PBPK Models for Fetal Drug Exposure: A Critical Assessment of Current Approaches and Regulatory Readiness. [PDF]

J Clin Pharmacol
Dallmann A, Butler A, Fischer-Holzhausen S, Kerwash E, Macente J, Nauwelaerts N, Illamola SM, Rowland Yeo K, Knöchel J.   +8 more
europepmc   +1 more source

Skin physiologically based pharmacokinetic modeling: current research progress, software comparison, and future perspectives. [PDF]

Drug Deliv
Li Y, Li Y, Liu YX, Zhang HF, Zhang S, Kuang Y, Pei Q, Yang G.   +7 more
europepmc   +1 more source

A Physiologically Based Pharmacokinetic Model to Predict Potential Drug-Drug Interactions of TPN171, a Novel Phosphodiesterase Type 5 Inhibitor. [PDF]

CPT Pharmacometrics Syst Pharmacol
Tian G, Chen T, Li L, Wang Z, Yang H, Juan J, Duan Y, Pei J, Jia J.   +8 more
europepmc   +1 more source

Sex-Related Differences in Physiologically-Based Biopharmaceutics Modeling. [PDF]

CPT Pharmacometrics Syst Pharmacol
Chavarría-Rojas M, Murshed M, Lorier M, Fotaki N, Ibarra M.   +4 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Model of Brigatinib in Healthy Volunteers and Patients With Cancer. [PDF]

CPT Pharmacometrics Syst Pharmacol
Xu Y, Hu X, Zhao P, Wang L, Ruan Z, Jiang B, Lou H.   +6 more
europepmc   +1 more source