Results 131 to 140 of about 65,658 (308)
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.Higher maternal BMI before and during early pregnancy is associated with lower prolactin levels across gestation and a reduced prolactin rise. Prolactin in pregnancy may reflect maternal metabolic health and has potential relevance to lactation outcomes.
Kate Rassie +11 more
wiley +1 more source
Journal of Pharmacy and Bioallied SciencesThis case study discusses the treatment of primary infertility in a 29-year-old female with a case of polycystic ovarian syndrome (PCOS) who presented to the Infertility Clinic at Wardha, Maharashtra, with a 2-year history of failed conception.
Puja Dhamija +5 more
doaj +1 more source
Pharmacological management of Polycystic Ovarian Syndrome
, 2020 PCOS is a common reproductive and endocrinological disorder that affect women of reproductive age. oligomenorrhea, excess hair growth, acne, and obesity can occur in women with PCOS.
Momoh, Ewere Winifred
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PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes
British Journal of Pharmacology, EarlyView.Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier +9 more
wiley +1 more source
Targeting hexokinase 2 to induce breast cancer cell senescence
British Journal of Pharmacology, EarlyView.Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof +8 more
wiley +1 more source
Cardiometabolic Risk in First Degree Relatives of Women With Polycystic Ovary Syndrome (PCOS)
Clinical Endocrinology, EarlyView.ABSTRACT Objective Polycystic ovary syndrome (PCOS) is a common multisystem disorder with reproductive, cardiometabolic and psychological implications. Genetic factors play a role in the pathogenesis of PCOS. We sought to investigate the cardiometabolic health of first degree relatives (FDR) of women with PCOS.
Su Jen Chua +8 more
wiley +1 more source
Novel applications possibilities for phase-change materials and devices
, 2016 Phase-change materials and devices are most widely known for their use in optical and electrical non-volatile memory applications. Recently however the potential has been demonstrated for using phase-change materials and devices for a range of novel ...
Wang, L +8 more
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The Relationship Between Polycystic Ovary Syndrome (PCOS) and Depression
Clinical Endocrinology, EarlyView.ABSTRACT Objective Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder, frequently accompanied by psychological comorbidities including depression. The aim of this narrative review is to summarise the latest research regarding potential contributors to and underpinning mechanisms of this relationship.
Asimina I. Karampela, Maralyn Druce
wiley +1 more source
Clinical Endocrinology, EarlyView.ABSTRACT Objective To evaluate the effect of inositol supplementation on biochemical hyperandrogenism in women with polycystic ovary syndrome (PCOS) and to explore whether metabolic phenotype modifies the endocrine response. Design Systematic review and meta‐analysis of randomized controlled trials conducted in accordance with PRISMA guidelines ...
Daniele Tienforti +10 more
wiley +1 more source