Metformin-Functionalized Selenium Nanoparticles Restore Insulin Signaling and Metabolic Homeostasis in Letrozole-Induced Polycystic Ovary Syndrome Rat Model. [PDF]
Ermis U +5 more
europepmc +1 more source
Organoids: Current Applications and Future Directions
Organoids are three‐dimensional multicellular structures derived from stem cells or primary tissues that recapitulate key structural and functional features of native organs. Advances in stem cell biology, biomaterials, and bioengineering have established organoids as powerful platforms for studying human development and disease mechanisms, drug ...
Yueqi Leng +14 more
wiley +1 more source
The impact of subclinical hypothyroidism on core reproductive hormones and ovarian endocrine status in patients with polycystic ovary syndrome: a systematic review and meta-analysis. [PDF]
Liu Y, Deng T, Zhao P.
europepmc +1 more source
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng +4 more
wiley +1 more source
Adult psychological outcomes among women with different adolescent PCOS presentations. [PDF]
Nowak-Ciołek MM +6 more
europepmc +1 more source
Abstract Coral reefs are increasingly threatened by local and global stressors. Traditional visual reef monitoring methods are time‐intensive and provide only a snapshot of reef condition. Recent efforts aim to measure reef metabolism, or the balance of net community production (NCP) and net community calcification (NCC), as coral reef carbonate ...
Emily M. Hammermeister +9 more
wiley +1 more source
Anti-Müllerian Hormone and Metabolic-Hormonal Profiles in Women With and Without Polycystic Ovary Syndrome: A Population-Based Study. [PDF]
Ramezani Tehrani F +5 more
europepmc +1 more source
Evaluation of Timing and Amplitude Biases in the Controls of Simulated Southern Ocean pCO2
Abstract The Southern Ocean is a major sink for atmospheric carbon dioxide and critical to the current and future carbon cycle. This net annual CO2 ${\text{CO}}_{2}$ flux reflects the balance of strong seasonal variability characterized by opposing periods of winter outgassing and summer uptake. Using a simple framework, we evaluate how model biases in
Seth M. Bushinsky +11 more
wiley +1 more source
Simulated Ocean Oxygen Under Miocene Boundary Conditions
Abstract The Miocene Climatic Optimum (MCO; 16.9–14.7 Ma) was a warm interval with atmospheric CO2 ${\text{CO}}_{2}$ comparable to end‐of‐21st‐century projections under intermediate emission scenarios. Proxy records indicate the Oxygen Minimum Zone (OMZ) in the Eastern Tropical Pacific (ETP) was small or non‐existent during the MCO, expanding only when
James R. Berg +5 more
wiley +1 more source

