Results 71 to 80 of about 49,971 (256)

Association of Organochlorine Pesticide Exposure as Endocrine Disruptors with Polycystic Ovarian Syndrome in North India

Journal of Mid-Life Health
Aim and Background: This study explores the correlation of blood levels of organochlorine pesticides (OCPs) between PCOS and non-PCOS women, considering the endocrine-disrupting properties of OCPs and their potential role in PCOS pathogenesis.
Ruchika Garg, Binita Goswami, Kamna Singh, Shaifali Singh, Prabhat Agrawal, Prashant Gupta, Urvashi Verma   +6 more
doaj   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

The Role of High Cxcl11 Expression in Ovarian Dysfunction Through NF‐κB and AKT Pathways in a Thin Endometrium Mouse Model

iNew Medicine, EarlyView.
Thin endometrium upregulates Cxcl11, which polarizes ovarian macrophages via NF‐κB/AKT, impairing ovarian function. A new uter‐ovarian signaling axis is identified. ABSTRACT Objective Thin endometrium (TE) is a recognized cause of female infertility, primarily associated with impaired uterine receptivity.
Yulu Yang, Fei Tang, Zihan Meng, Yunxi Bao, Jujun Han, Xiaohua Jiang, Jianye Wang, Ying Wang, Zhaolian Wei   +8 more
wiley   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder

JCPP Advances, EarlyView.
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista, Patrizia Ventura, Samuele Cortese, Paolo Trerotoli, Alessandra Di Gioia, Lucia Margari   +5 more
wiley   +1 more source

Health related quality of life in women with Polycystic Ovary Syndrome (PCOS)

Payesh, 2012
Objective (s): Polycystic ovary syndrome (PCOS) is a disorder of hyperandrogenemia and chronic anovulation which affects 5-10% of all women. The PCOS symptoms such as hirsutism, irregular menses, obesity and infertility are a major source of ...
Leila Amini, Naemeh Seyedfatemi, Ali Montazeri, Zohreh Mahmoodi, Soheila Arefi, Fatemeh Hosseini, Homa Sadeghi Avval-Shahr, Behzad Ghorbani   +7 more
doaj  

NTECARS: A Nonthermal Equilibrium CARS Spectra Fitting Code

Journal of Raman Spectroscopy, EarlyView.
We present NTECARS, an open‐source code written in Julia for the calculation and fitting of CARS spectra under nonequilibrium conditions. Rovibrational distributions can be flexibly modeled and fitted for different use cases. The code currently implements CO2$$ \mathrm{C}{\mathrm{O}}_2 $$ and N2$$ {\mathrm{N}}_2 $$ molecules and is validated under ...
Christian A. Busch, Uwe Czarnetzki
wiley   +1 more source

PCOS HASTALARINDA BİYOELEKTRİK İMPEDANS ANALİZİ İLE DEĞERLENDİRİLEN VÜCUT KOMPOZİSYONLARININ; METABOLİK, HORMONAL VE ANTROPOMETRİK ÖLÇÜMLERLE KARŞILAŞTIRILMASI

Journal of Contemporary Medicine, 2021
Amaç: Bu çalışmada, PCOS’lu ve sağlıklı kontrol grubu hastalarında, vücut kompozisyon parametreleri BIA (Biyoelektrik İmpedans Analizi) ile ölçülerek, metabolik, antropometrik ve hormonal parametrelerle karşılaştırılmıştır.
Mahmut Altuntaş, Hüseyin Aksoy
doaj  

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Isotretinoin and Hidradenitis Suppurativa a Conflictual Binomial: Investigation on Differential Response Rate Between Inflammatory and Follicular Phenotype

JEADV Clinical Practice, EarlyView.
A cohort of 21 HS patients treated with isotretinoin was enrolled in this study. The main outcome was HISCR50 achievement at week 16. Overall, 2/12 patients affected by follicular phenotype of HS and 2/9 patients affected by inflammatory phenotype of HS achieved HISCR50 at week 16. No significant difference was found in response to isotretinoin between
Maria Vittoria Cannizzaro, Flaminia Antonelli, Dalma Malvaso, Federica Pellegrini, Elena Ippoliti, Niccolò Gori, Ketty Peris   +6 more
wiley   +1 more source