Words do matter:A systematic review on how different terminology for the same condition influences management preferences [PDF]
, 2017 OBJECTIVES: Changing terminology for low-risk, screen-detected conditions has now been recommended by several expert groups in order to prevent overdiagnosis and reduce the associated harms of overtreatment. However, the effect of terminology on patients'
Barratt, Alexandra L +4 more
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Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development
Advanced Science, EarlyView.The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu +12 more
wiley +1 more source
Advances in the management of osteopenia: a case series
Journal of Medical Case ReportsBackground Osteopenia is a pre-pathological condition characterized by reduced bone mineral density that may lead to increased fracture risk and to the onset of osteoporosis. Standard treatments for managing osteopenia include supplementation of calcium,
Maurizio Nordio, Roberto Baldelli
doaj +1 more source
Frontiers in EndocrinologyIntroductionPolycystic ovary syndrome (PCOS) is associated with increased cardiometabolic risk in young women of reproductive age. There are limited studies on atherogenic dyslipidemia, inclusive of triglycerides (TG), Apolipoprotein (apo) B-lipoproteins
Xiaoying Wu +11 more
doaj +1 more source
Polycystic Ovary Syndrome: Pathogenesis, health consequences, and treatment of PCOS in relation to insulin resistance [PDF]
, 2012 The purpose of this paper is to present a review of the current research on polycystic ovary syndrome (PCOS). PCOS is one of the most common endocrine disorders in women of reproductive age, affecting 5-10% of the population. Despite its prevalence, PCOS
Bernier, Danielle
core +2 more sources
Does Metformin combined with Clomiphene Citrate improve fertility related outcomes in Clomiphene resistant women with PCOS : a systematic review [PDF]
, 2014 Peer reviewedPublisher ...
Colleran, Rebecca +5 more
core +2 more sources
Advanced Science, EarlyView.We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim +6 more
wiley +1 more source
Myo-Inositol and Its Derivatives: Their Roles in the Challenges of Infertility
BiologyMyo-inositol (MYO) and D-chiro-inositol (DCI) are the two most significant isomeric forms of inositol, playing a critical role in intracellular signaling. MYO is the most abundant form of inositol in nature; DCI is produced from MYO through epimerization
Martina Placidi +4 more
doaj +1 more source
Pregravid preparation of women with polycystic ovary syndrome.
Репродуктивная эндокринология, 2020 Polycystic ovary syndrome (PCOS) is a significant component in the structure of diseases that cause female infertility, and the most common cause of ovarian dysfunction in women of reproductive age.
Г. О. Ісламова
doaj +1 more source
Individual 17-Hydroxyprogesterone Responses to hCG Are Not Correlated With Follicle Size in Polycystic Ovary Syndrome. [PDF]
, 2019 Context:In women with polycystic ovary syndrome (PCOS), 17-hydroxyprogesterone (17-OHP) responses to gonadotropin stimulation vary from increased to indistinguishable compared with normal controls.
Chang, R Jeffrey +5 more
core +1 more source