Results 21 to 30 of about 179,308 (302)
Coordination of planar cell polarity pathways through Spiny-legs
eLife, 2015 Morphogenesis and physiology of tissues and organs requires planar cell polarity (PCP) systems that orient and coordinate cells and their behaviors, but the relationship between PCP systems has been controversial.
Abhijit A Ambegaonkar, Kenneth D Irvine
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Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation [PDF]
, 2006 The planar cell polarity (PCP) pathway is conserved throughout evolution, but it mediates distinct developmental processes. In Drosophila, members of the PCP pathway localize in a polarized fashion to specify the cellular polarity within the plane of the
Brinkman, Brendan C. +9 more
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A mammalian Wnt5a-Ror2-Vangl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis. [PDF]
, 2020 Alveolar formation increases the surface area for gas-exchange and is key to the physiological function of the lung. Alveolar epithelial cells, myofibroblasts and endothelial cells undergo coordinated morphogenesis to generate epithelial folds (secondary
Chou, Yu-Ting +7 more
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Theoretical tool bridging cell polarities with development of robust morphologies
eLife, 2018 Despite continual renewal and damages, a multicellular organism is able to maintain its complex morphology. How is this stability compatible with the complexity and diversity of living forms?
Silas Boye Nissen +3 more
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Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice [PDF]
, 2018 Fractures are a common comorbidity in children with the neural tube defect (NTD) spina bifida. Mutations in the Wnt/planar cell polarity (PCP) pathway contribute to NTDs in humans and mice, but whether this pathway independently determines bone mass is ...
A Kamalakar +66 more
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BMJ Case Reports, 2019 A 54-year-old Caucasian man presented to the emergency department complaining of worsening productive cough, weight loss and left-sided chest pain lasting 1 month. He did not have a fever. He had a medical history of HIV diagnosed 22 years ago and had not been receiving any antiretroviral ...
Emad, Abu Sitta +3 more
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Frontiers in Pharmacology, 2022 Nonalcoholic fatty liver disease (NAFLD) is prevalent worldwide, while no pharmaceutical treatment has been approved. Natural herbs are promising for their amelioration effect on lipid metabolism.
Jieyi Wang +14 more
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An XPS Investigation of Thermal degradation and Charring of Cross-linked Polyisoprene and Polychloroprene [PDF]
, 2001 Our interest in butadiene-containing polymers had led to an investigation of the thermal degradation of polyisoprene, PIP, and polychloroprene, PCP. The connection between cross-linking and thermal stability through an examination of PIP and PCP has been
Hao, JIanwei +2 more
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Ebola Virus Maintenance: If Not (Only) Bats, What Else?
Viruses, 2018 The maintenance mechanisms of ebolaviruses in African forest ecosystems are still unknown, but indirect evidences point at the involvement of some bat species. Despite intense research, the main bat-maintenance hypothesis has not been confirmed yet.
Alexandre Caron +5 more
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Frontiers in Microbiology, 2021 Pneumocystis pneumonia (PCP) is an opportunistic infection that commonly occurs in immunocompromised individuals. A definite diagnosis of PCP can be made only when the organism is identified in a respiratory specimen.
Patsharaporn T. Sarasombath +7 more
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