Correction of the neuropathogenic human apolipoprotein E4 (APOE4) gene to APOE3 in vitro using synthetic RNA/DNA oligonucleotides (chimeraplasts) [PDF]
Apolipoprotein E (apoE) is a multifunctional circulating 34-kDa protein, whose gene encodes single-nucleotide polymorphisms linked to several neurodegenerative diseases.
Dickson, JG +3 more
core +1 more source
Mapping the locus for ocular melanosis in Cairn Terriers
Abstract Objective To map the disease locus for familial ocular melanosis (OM) in the Cairn Terrier. Animals Studied Cairn Terriers with OM and normal control dogs. Procedure A genome‐wide association study (GWAS) was performed using 63 OM‐affected and 31 control Cairn Terriers, followed by haplotype analysis.
Paige A. Winkler +5 more
wiley +1 more source
Comparison of Microscopy and PCR-RFLP for detection of Anaplasma marginale in carrier cattle
Background and Objectives: In Iran, anaplasmosis is normally diagnosed with traditional Giemsa staining method. This is not applicable for identification of the carrier animals. The aim of this study was to compare the detection of Anaplasma marginale in
V Noaman, P Shayan
doaj
Human papillomavirus detection and typing using a nested-PCR-RFLP assay
BACKGROUND: It is clinically important to detect and type human papillomavirus (HPV) in a sensitive and specific manner. OBJECTIVES: Development of a nested-polymerase chain reaction-restriction fragment length polymorphism (nested-PCR-RFLP) assay to ...
Janaina Coser +4 more
doaj +1 more source
Prevalence of QoI resistance and mtDNA diversity in the Irish Zymoseptoria tritici population [PDF]
peer-reviewedThe emergence and spread of Quinone outside Inhibitor (QoI) fungicide resistance in the Irish Zymoseptoria tritici population in the early 2000s had immediate impacts on the efficacy of the entire group of fungicides for the control of ...
Bucar, D.E. +5 more
core +1 more source
Commodity risk assessment of Vitis spp. plants from Moldova
Abstract The European Commission requests EFSA to provide scientific opinions in the field of plant health in accordance with Article 29 of Regulation (EC) No 178/2002. Annex VI of Commission Implementing Regulation (EU) 2019/2072 lists plants, plant products and other objects whose introduction into the Union from certain third countries is prohibited.
EFSA Panel on Plant Health (PLH) +37 more
wiley +1 more source
This study highlights how cervical carcinoma progression is shaped by immune–tumor interactions within the TME. M2‐TAM infiltration, regulated through STAT3/NF‐κB and linked to CXCL12–CXCR4, promotes immune suppression, angiogenesis, and poor survival.
George A. Lira +11 more
wiley +1 more source
Blood Meal Identification in Field-Captured Sand flies: Comparison of PCR-RFLP and ELISA Assays
Background: We aimed to develop a PCR-RFLP assay based on available sequences of putative vertebrate hosts to identify blood meals ingested by field female sand fly in the northwest of Iran.
N Maleki-Ravasan +5 more
doaj
A point mutation in the splice donor site of intron 7 in the as2-casein encoding gene of the Mediterranean River buffalo results in an allele-specific exon skipping [PDF]
The CSN1S2 cDNA of 10 unrelated Mediterranean River Buffaloes reared in Southern Italy was amplified by RT-PCR, while the region from the 6th to the 8th exon of the CSN1S2 gene was amplified from genomic template.
COLETTA A. +6 more
core +1 more source
Abstract Premise Plants in sympatric populations with congeners may have evolved tolerance to the negative effects of heterospecific pollen (HP) through selection on female or male reproductive traits. If so, then the degree of HP tolerance may vary depending on the co‐existence history of the maternal and paternal plant source populations.
Yusuke Hoshino +3 more
wiley +1 more source

