Results 61 to 70 of about 43,727 (186)

A novel selective stabilizer of the ryanodine receptor 2 prevents stress‐induced ventricular arrhythmias without impairing cardiac function

British Journal of Pharmacology, Volume 183, Issue 15, Page 4321-4343, August 2026.
Abstract Background and Purpose Aberrant activation of type 2 ryanodine receptors (RyR2) causes lethal arrhythmias, such as catecholaminergic polymorphic ventricular tachycardia (CPVT). Developing drugs that suppress RyR2 hyperactivation may be key to novel arrhythmia treatments.
Nagomi Kurebayashi, Masami Kodama, Hana Inoue, Masato Konishi, Masami Sugihara, Takashi Murayama, Ryosuke Ishida, Koichiro Ishii, Shuichi Mori, Yukari Endo, Xi Zeng, Yukiko U. Inoue, Takayoshi Inoue, Satoru Noguchi, Hajime Nishio, Eri Nakashima, Norio Suzuki, Noriko Nakaya, Ryushi Sato, Yuya Otori, Ayuna Tsutsumi, Mirei Takahashi, Takayuki Oka, Haruo Ogawa, Kayoko Kanamitsu, Hiroyuki Kusuhara, Utako Yokoyama, Junko Kurokawa, Hiroyuki Kagechika, Takashi Sakurai   +29 more
wiley   +1 more source

Genetic Landscape of Hearing Loss in Brazilian Patients Reveals Population‐Specific Variants and Clinical Correlations

Clinical Genetics, Volume 110, Issue 2, Page 210-226, August 2026.
The Burden: Hearing loss (HL) is the most prevalent sensory disorder globally, affecting 1.5 million individuals in Brazil. The Gap: While > 150 genes are linked to HL, the genetic architecture in underrepresented populations like Brazil is poorly defined. The Problem: This lack of data limits diagnostic yield and the application of precision medicine.
Stella Diogo‐Cavassana, Danillo Alencar‐Coutinho, Rafaella Abreu‐Oberhuber, Maria Eduarda Paramo‐Neto, Jeanne Oiticica, Ricardo Ferreira Bento, Ana Carla Batissoco, Karina Lezirovitz   +7 more
wiley   +1 more source

Genetic variability of myostatin and prolactin genes in popular goat breeds in Egypt

Journal of Genetic Engineering and Biotechnology, 2018
The genetic polymorphisms of two functional genes named: myostatin (MSTN) and prolactin (PRL) were investigated in three goat breeds (Barki, Damascus and Zaraibi) using Sanger nucleotide sequence and restriction fragment length polymorphism (RFLP ...
Sekena H. Abdel-Aziem, K.F. Mahrous, M.A.M. Abd El-Hafez, M. Abdel Mordy   +3 more
doaj   +1 more source

Development of PCR, LAMP and HRM‐Based Molecular Species Diagnostic Tools for Identifying Four Agricultural Pests in the Genus Helicoverpa (Lepidoptera: Noctuidae)

Journal of Applied Entomology, Volume 150, Issue 7, Page 900-913, August 2026.
ABSTRACT Within the subfamily Heliothinae, the genus Helicoverpa comprises several highly destructive agricultural pests, including H. armigera, H. assulta, H. punctigera and H. zea. These species cause significant global crop losses due to their wide host range, long‐distance migratory behaviour, and potential for interspecific hybridization.
Minseop Noh, Murtaza Khan, Minyoung Choi, Andreas Zwick, Juil Kim   +4 more
wiley   +1 more source

Restriction fragment length polymorphism analysis of isolates of infectious bursal disease viruses from Turkey

Veterinární Medicína, 2003
Infectious bursal disease Virus (IBDV) specific reverse transcriptase/polymerase chain recation (RT/PCR) positive 40 broiler bursa fabricius samples obtained from a commercially reared flock were investigated for genetic diversity by PCR-RFLP assay.
G. Ozbes, H.B. Ertas, A. Muzo
doaj   +1 more source

Occurrence of Antibodies Anti‐Toxoplasma gondii in Captive Non‐Human Primates From Pernambuco State, Brazil

Journal of Medical Primatology, Volume 55, Issue 4, August 2026.
ABSTRACT Wildlife captive populations are important tools for threatened species conservation, and early identification of diseases must be prioritized. In this study, we test for the presence of anti‐Toxoplasma gondii antibodies in non‐human primates at a Zoo from Pernambuco State, Brazil.
Marcio André Silva, Hilda Fátima Jesus Pena, Herbert Sousa Soares, Dênisson Silva Souza, Solange Maria Gennari, Jean Carlos Ramos Silva   +5 more
wiley   +1 more source

Molecular typing of Leishmania (Leishmania) amazonensis and species of the subgenus Viannia associated with cutaneous and mucosal leishmaniasis in Colombia: A concordance study

Biomédica: revista del Instituto Nacional de Salud, 2018
Introduction: Multilocus enzyme electrophoresis (MLEE) is the reference standard for the characterization of Leishmania species. The test is restricted to specialized laboratories due to its technical complexity, cost, and time required to obtain results.
Clemencia Ovalle-Bracho, Carolina Camargo, Yira Díaz-Toro, Marcela Parra-Muñoz   +3 more
doaj   +1 more source

Estudo do polimorfismo genético da α S1-caseína em cabras, no Estado de Pernambuco, Brasil = Study of the genetic polymorphism of the α S1-casein in goats of Pernambuco State, Brazil

Acta Scientiarum: Animal Sciences, 2007
O Estado de Pernambuco tem uma vocação pecuária, especialmente, para aexploração de caprinos. Dentre as proteínas, chamadas de caseínas, a αS1-caseína foi a primeira proteína comprovada com base no polimorfismo genético.
Ariosto Afonso da Silva, Manoel Adrião, George Chaves Jimenez, Madriano Christilis da Rocha Santos, Aurea Wischral, José Augusto Bastos Afonso   +5 more
doaj  

IDENTIFIKASI DAGING BABI MENGGUNAKAN METODE PCR-RFLP GEN Cytochrome b DAN PCR PRIMER SPESIFIK GEN AMELOGENIN (Pork Identification Using PCR-RFLP of Cytochrome b Gene and Species Specific PCR of Amelogenin Gene)

Agritech, 2013
A polymerase chain reaction–restriction fragment length polymorphism (PCR–RFLP) and species specific PCR methods had been applied for identifying pork in mixture of meat.
Yuny Erwanto, Sugiyono Sugiyono, Abdul Rohman, Mohammad Zainal Abidin, Dwi Ariyani   +4 more
doaj   +1 more source

Coagulase gene polymorphism of Staphylococcus aureus isolates: A study on dairy food products and other foods in Tehran, Iran

Food Science and Human Wellness, 2016
Coagulase is considered as a major determinant factor for the identification of Staphylococcus aureus strains. The 3′-end coding region of the coagulase (coa) gene contains a series of 81-bp tandem repeats, which differ in the number and location of ...
Mohammad Mehdi Soltan Dallal, Mohammad Reza Khoramizadeh, Solmaz Agha Amiri, Ali Akbar Saboor Yaraghi, Ramin Mazaheri Nezhad Fard   +4 more
doaj   +1 more source