Changing the frequency and spectra of chromosomal aberrations in Korean patients with acute leukemia in a tertiary care hospital. [PDF]
Park JH+7 more
europepmc +1 more source
A simple method for direct cloning and sequencing cDNA by the use of a single specific oligonucleotide and oligo(dT) in a polymerase chain reaction (PCR) [PDF]
Martin W. Berchtold
openalex +1 more source
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source
Background: Foot-and-mouth disease virus (FMDV) is a highly contagious viral infection of large ruminants. Despite the massive application of vaccines against FMDV, several outbreaks are still being reported in Africa and Asia.
Maged Gomaa Hemida+3 more
doaj +1 more source
A rapid method for the detection of potentially viableMycobacterium lepraein human biopsies: a novel application of PCR [PDF]
Sally A. Woods, Stewart T. Cole
openalex +1 more source
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
A note on the use of FTA™ technology for storage of blood samples for DNA analysis and removal of PCR inhibitors [PDF]
peer-reviewedFTA™ technology is widely used across many molecular disciplines for sample capture, storage and analysis. The use of this technology for the long-term storage of blood samples for DNA analysis was examined as well as its potential to ...
Hanrahan, James P+3 more
core
Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Chen‐xi Li, Zhong‐cheng Gong
wiley +1 more source
Specific amplification with PCR of a refractory segment of genomic DNA [PDF]
Tariq M. Haqqi+3 more
openalex +1 more source
High throughput sequencing analysis of RNA libraries reveals the influences of initial library and PCR methods on SELEX efficiency. [PDF]
The systemic evolution of ligands by exponential enrichment (SELEX) technique is a powerful and effective aptamer-selection procedure. However, modifications to the process can dramatically improve selection efficiency and aptamer performance.
Burnett, John C+6 more
core