Results 131 to 140 of about 4,982,154 (391)

Nomogram-derived prediction of pathologic complete response (pCR) in breast cancer patients treated with neoadjuvant chemotherapy (NCT) [PDF]

, 2020
Shengyu Pu, Ke Wang, Yang Liu, Xiaoqin Liao, Heyan Chen, Jianjun He, Jian Zhang   +6 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Development of real-time PCR and hybridization methods for detection and identification of thermophilic Campylobacter spp. in pig faecal samples [PDF]

, 2005
Aims: To develop a real-time (rt) PCR for species differentiation of thermophilic Campylobacter and to develop a method for assessing co-colonization of pigs by Campylobacter spp. Methods and results: The specificity of a developed 5’nuclease rt-PCR for
Al Rashid S.T., Cloak O.M., Hani E.C., Hunt J.M., Linton D., Manser P.A., Munroe D., Ng L.-K., Penner J.L., Totten P.A., Wilson D.L.   +10 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Influence of Container Volume and Cuttings Size on the Growth Parameters of Seedlings with a Closed Root System of Two Poplar Genotypes in the Voronezh Region

International Journal of Plant Biology
This study examined the bioproductivity of two poplar genotypes propagated by single-tree stem cuttings. The experiment compared variants using cuttings of different lengths (10–22 cm) and containers with volumes from 1 to 3 L. It was found that the best
Peter Evlakov, Alexey Tseplyaev, Anna Popova, Vladimir Zapletin, Vladlena Ryzhkova, Lyudmila Repnikova, Konstantin Zhuzhukin   +6 more
doaj   +1 more source

Learning perceptual chunks for problem decomposition [PDF]

, 2001
How students learn to use diagrammatic representations is an important topic in the design of effective representations for problem solving or conceptual learning, but few good models of their learning exist.
Cheng, PCH, Gobet, F, Lane, PCR
core   +3 more sources

Acute febrile illness is associated with Rickettsia spp infection in dogs [PDF]

, 2015
BACKGROUND: Rickettsia conorii is transmitted by Rhipicephalus sanguineus ticks and causes Mediterranean Spotted Fever (MSF) in humans. Although dogs are considered the natural host of the vector, the clinical and epidemiological significance of R ...
A Cascio, A Estrada-Pena, A Mannelli, A Mura, A Ortuno, A Rojas, A Torina, A Torina, A Torina, A Znazen, Alessandra Caprì, AM Gasser, BA Stillman, C Colomba, C Riera, C Rovery, CP Ober, D Otranto, D Otranto, D Otranto, E Beeler, E Sanger, EB Breitschwerdt, F Segura-Porta, FJ Marquez, G Baneth, G Baneth, G Baneth, G Vitale, GB Andrade, GM Giammanco, GM Giammanco, H Inokuma, J Fuente de la, JC Garcia-Garcia, L Solano-Gallego, L Solano-Gallego, L Solano-Gallego, L Solano-Gallego, L Solano-Gallego, L Solano-Gallego, L Solano-Gallego, Laia Solano-Gallego, M Bernabeu-Wittel, M Rene-Martellet, M Sarih, Marco Caldin, Maria Grazia Pennisi, ME Eremeeva, ME Mylonakis, Michele Trotta, ML Levin, ML Levin, N Alexandre, N Cardenosa, NY Salem, P Brouqui, P Brouqui, P Parola, P Parola, PJ Kelly, S Delgado, S Harrus, S Harrus, S Santibanez, SE Little, T Beninati, T Furlanello, Tommaso Furlanello, WL Nicholson   +69 more
core   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Point-Counterpoint: Large Multiplex PCR Panels Should Be First-Line Tests for Detection of Respiratory and Intestinal Pathogens [PDF]

, 2015
Paul C. Schreckenberger, Alexander J. McAdam   +1 more
openalex   +1 more source

Measurement of Transgene Copy Number in Plants Using Droplet Digital PCR [PDF]

, 2021
Yaomin Cai, Quentin M. Dudley, Nicola J. Patron   +2 more
openalex   +1 more source