Results 141 to 150 of about 3,963,364 (363)

In-House RT-PCR Assay for Detection of Human Immunodeficiency Virus Type 1 Infection [PDF]

open access: yes, 2009
Serologic assays are commonly used for screening (ELISA) and for confirmation (Western blot) of HIV-1 infection; however, both assays have potentially yielded the false-positive or false-negative results.
Bela, B. (Budiman)   +4 more
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Detección molecular de Mycoplasma spp. en gatos con y sin signos clínicos compatibles con Complejo Respiratorio Felino

open access: yesAb Intus
El complejo respiratorio felino (CRF) es una enfermedad distribuida mundialmente y común en lugares donde hay una alta concentración de gatos. Los agentes comúnmente asociados al CRF son Herpesvirus felino, Calicivirus felino, Chlamydophila felis ...
Cecilia Hurrass   +3 more
doaj   +1 more source

PCR-RFLP analysis of cpDNA and mtDNA in the genus Houttuynia in some areas of China

open access: gold, 2006
Wei Wu   +5 more
openalex   +1 more source

A two stage model for quantitative PCR [PDF]

open access: green, 2006
Emily Stone, John Goldes, Martha Garlick
openalex   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

T Oligo-Primed Polymerase Chain Reaction (TOP-PCR): A Robust Method for the Amplification of Minute DNA Fragments in Body Fluids. [PDF]

open access: yes, 2017
Body fluid DNA sequencing is a powerful noninvasive approach for the diagnosis of genetic defects, infectious agents and diseases. The success relies on the quantity and quality of the DNA samples.
Chen, Chien-Jen   +8 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

OPTIMIZING MOLECULAR TECHNIQUES FOR ACCURATE EXAMINATION OF LEPTOSPIRA SPECIES: A COMPREHENSIVE PRIMER FOR RESEARCHERS

open access: yesJournal of Vocational Health Studies
Background: Leptospirosis is a potentially life-threatening disease caused by bacteria of the genus Leptospira. The accurate identification and characterization of Leptospira species are critical for disease surveillance, outbreak investigation, and ...
Aldiana Astuti, Farida Dwi Handayani
doaj   +1 more source

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