Results 131 to 140 of about 2,958,232 (316)

Primers used for real-time RT-PCR

open access: yes, 2016
Primers used for real-time RT ...
Kohta Ohnishi (387891)   +3 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

PCR in Leprosy.

open access: yesJapanese journal of leprosy, 2001
Detection of M. leprae DNA using PCR is very sensitive enough to detect very few number of bacilli which are not recognized by acid-fast staining method. Because the detection of M. leprae is crucial for the diagnosis of leprosy, PCR method has been expected to make a diagnosis easy and precise. A new pair of PCR primers for M.
openaire   +3 more sources

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

PCR-GLOBWB_model: eWaterCycle Development Version

open access: yes, 2016
<p>This is the alpha release of the PCR-GLOBWB model, as used in the eWaterCycle project.</p> <p>This version contains a BMI interface for PCRGlobWB, among other improvements.</p> <p>It is strongly advised to use the main ...
Edwin Sutanudjaja   +7 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Detecting meat-and-bone meal in ruminant’s feeds by species-specific PCR

open access: yes, 2012
[[abstract]]Bovine spongiform encephalopathy, first identified in the UK in 1986, may have arisen from feeding scrapie infected meat-and-bone meal (MBM) to cattle that was produced under sub-optimal conditions.
溫秋明   +5 more
core  

PCR-GLOBWB_model: PCR-GLOBWB version v2.1.0_beta_1

open access: yes, 2017
<p>PCR-GLOBWB (PCRaster Global Water Balance) is a large-scale hydrological model intended for global to regional studies and developed at the Department of Physical Geography, Utrecht University (Netherlands).</p> <p>Contact: Edwin ...
Edwin Sutanudjaja
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

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