Results 251 to 260 of about 3,963,364 (363)

<i>Leptospira</i> Species Infection and Seropositivity in Domestic Livestock and Feral Swine in Puerto Rico. [PDF]

Transbound Emerg Dis
Dirsmith KL, Nally JE, Sutherland G, Hamond C, Galloway RL, LeCount K, Anderson T, Soltero FV, Rivera-García S, Novak V, Olivieri-Cintrón GE, Gruver K, Brown VR, Glassey C, McKinley AS, Candelaria O, Stephens L, Schafer IJ.   +17 more
europepmc   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Real-Time PCR Detection of <i>Alicyclobacillus acidoterrestris</i> in Fruit Juice: Method Validation and Implications for Guaiacol-Related Spoilage. [PDF]

Foods
Lin SL, Valdrez MM, Chang SH.
europepmc   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Lateral flow-based assay for simple and rapid visual detection of Asian-type DEL. [PDF]

PeerJ
Bunpoom Y, Leelayuwat C, Tippayawat P, Wongwattanakul M, Simtong P.   +4 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Non-BRCA germline pathogenic variants and response to neoadjuvant systemic therapy in triple-negative breast cancer patients enrolled in a prospective clinical trial. [PDF]

Breast Cancer Res Treat
Lee KL, Yam C, Zhao L, Bassett RL, Song X, Thompson AM, White JB, Layman RM, Huo L, Gutierrez AM, Valero V, Ueno NT, Litton JK, Zhang J, Ravenberg E, Korkut A, Adrada BE, Candelaria RP, Rauch GM, Tripathy D, Shaitelman SF, Arun BK.   +21 more
europepmc   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

The Effects of a Dietary Supplement on Bloating and Digestive Health

Current Developments in Nutrition
Shelly N Hester, Rebecca Major, Tanner M Gibb, Helen Knaggs, Melanie Riggs, Barrie Drewitt   +5 more
doaj   +1 more source

Evaluation of Droplet Digital PCR Assay for the Detection of Microsatellite Instability in Colorectal, Gastric, and Endometrial Cancers. [PDF]

Diagnostics (Basel)
Chung Y, Oh S, Nam SK, Kim H, Lee C, Kang GH, Oh HJ, Lee HS, Park KU.   +8 more
europepmc   +1 more source