Results 91 to 100 of about 4,063 (166)

Synaptic and extrasynaptic distribution of NMDA receptors in the cortex of Alzheimer's disease patients

open access: yesAlzheimer's &Dementia, Volume 20, Issue 12, Page 8231-8245, December 2024.
Abstract BACKGROUND Synaptic and extrasynaptic distribution of N‐methyl‐D‐aspartate receptors (NMDARs) has not been addressed in the brain from Alzheimer´s disease (AD) subjects, despite their contribution to neurodegeneration. METHODS We have developed a protocol to isolate synaptic and extrasynaptic membranes from controls and AD frontal cortex.
Sergio Escamilla   +7 more
wiley   +1 more source

Bending Collapse of Thin Plate with Corrugated Cross-Section [PDF]

open access: yes, 2010
In this paper, the collapse behaviors of thin plate with corrugated cross-section subjected to three-point bending are studied by using the finite element method.
増田 健一, 陳 玳珩
core   +2 more sources

Targeting proliferating cell nuclear antigen enhances ionizing radiation‐induced cytotoxicity in prostate cancer cells

open access: yesThe Prostate, Volume 84, Issue 16, Page 1456-1467, December 2024.
Abstract Background Proliferating cell nuclear antigen (PCNA) is essential for DNA replication and repair, cell growth, and survival. PCNA also enhances androgen receptor (AR) signaling in prostate cancer (PC) cells. We identified a PCNA interaction protein (PIP) box at the N‐terminal domain of AR and developed a small peptide PCNA inhibitor R9‐AR‐PIP ...
Shan Lu   +3 more
wiley   +1 more source

Epigenome‐wide association study of prostate cancer in African American men identified differentially methylated genes

open access: yesCancer Medicine, Volume 13, Issue 16, August 2024.
Abstract Introduction Men with African ancestry have the highest incidence and mortality rates of prostate cancer (PCa) worldwide. Methods This study aimed to identify differentially methylated genes between tumor vs. adjacent normal and aggressive vs. indolent PCa in 121 African American patients.
Anders Berglund   +23 more
wiley   +1 more source

Upaya Joint Nations Program on Hiv/aids (Unaids) Dalam Penanganan Hiv/aids Di Nigeria [PDF]

open access: yes, 2017
This research explains the role of International organizations in dealing with HIV / AIDS that occurred in Nigeria in 2010. One of the countries with highest HIV / AIDS transmission rate is Nigeria.
Iskandar, I. (Irwan)   +1 more
core  

Matrix Algebras with a Certain Compression Property I

open access: yes, 2019
An algebra $\mathcal{A}$ of $n\times n$ complex matrices is said to be projection compressible if $P\mathcal{A}P$ is an algebra for all orthogonal projections $P\in\mathbb{M}_n(\mathbb{C})$.
Cramer, Zachary   +2 more
core   +1 more source

Increased α2,3‐sialyl N‐glycosylated prostate‐specific membrane antigen (PSMA) in post‐DRE urine is associated with high grade group prostate cancer

open access: yesThe Prostate, Volume 84, Issue 11, Page 1067-1075, August 2024.
Abstract Introduction Aberrant glycosylation of proteins is an important hallmark in multiple cancers. Prostate‐specific membrane antigen (PSMA), a highly glycosylated protein with 10 N‐linked glycosylation sites, is an Food and Drug Administration approved theranostic for prostate cancer. However, glycosylation changes in PSMA that are associated with
Stephen Mackay   +6 more
wiley   +1 more source

Electronic beam switching commutator Patent [PDF]

open access: yes, 1967
Using electron beam switching for brushless motor ...
Studer, P. A.
core   +1 more source

ID factors regulate the ability of Müller glia to become proliferating neurogenic progenitor‐like cells

open access: yesGlia, Volume 72, Issue 7, Page 1236-1258, July 2024.
Main Points ID4 transcription is regulated by several pathways that are active during Müller glia reprogramming. ID4 activity is necessary for Müller glia to become progenitor‐like and proliferate, but ID1/2/3 suppresses differentiation of progeny into neuron‐like cells.
Olivia B. Taylor   +4 more
wiley   +1 more source

Opposing roles of TGFβ and BMP signaling in prostate cancer development [PDF]

open access: yes, 2017
SMAD4 constrains progression of Pten-null prostate cancer and serves as a common downstream node of transforming growth factor β (TGFβ) and bone morphogenetic protein (BMP) pathways.
Chang, Qing   +13 more
core   +1 more source

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