Results 1 to 10 of about 661,450 (98)
Molecular dynamics insights into the redox effects on PD-1/PD-L1 and PD-1/PD-L2 interactions [PDF]
Scientific ReportsThe PD-1/PD-L1/PD-L2 immune checkpoint plays a critical role in regulating immune responses, and its dysfunction is implicated in immune evasion by cancer cells.
Rasulbek Mashalov +3 more
doaj +2 more sources
Association of PD-1 gene polymorphisms and serum soluble PD-1 levels with type 1 diabetes mellitus susceptibility in a Chinese Han cohort: a case-control study [PDF]
Frontiers in ImmunologyBackgroundThe programmed cell death 1 (PD-1)/PD-L1 pathway plays a critical role in immune tolerance and has been implicated in type 1 diabetes mellitus (T1DM).
Renhao Zhao +6 more
doaj +2 more sources
نقش PD-1/ PD-L1 و Anti-PD-1/ PD-L1 در پیشرفت و سرکوب سرطان [PDF]
Majallah-i Dānishkadah-i Pizishkī-i Dānishgāh-i ̒ Ulūm-i Pizishkī-i Mashhad., 2023 نقاط کنترل ایمنی (Immune checkpoints) مجموعه ای از گیرنده های تنظیمی می باشند که باعث کنترل پاسخ های ایمنی، حفظ تولرانس و هموستاز می شود. سلول های توموری می توانند با به خدمت گرفتن این نقاط از دسترس پاسخ های اختصاصی ضد تومورال بگریزند و گسترش پیدا کنند ...
نرگس عبدالهی +3 more
doaj +1 more source
Towards European Transitions: Indicators for the Development of Marginal Urban Regions
Land, 2022 Urban transitions and urban-scape have been heavily impacted by the COVID-19 pandemic and will likely be affected by the current Ukrainian-Russian conflict.
Rubina Canesi, Giuliano Marella
doaj +1 more source
Applied Sciences, 2023 Space debris represent a threat to satellites in orbit around Earth. In the case of impact, satellites can be subjected to damage spanning from localized craterization to subsystem failure, to complete loss of the vehicle; large collision events may lead
Lorenzo Olivieri +3 more
doaj +1 more source
Applied Sciences, 2023 Additive manufacturing (AM) is becoming increasingly relevant among established manufacturing processes. AM parts must often be recognized to sort them for part- or order-specific post-processing.
Jonas Conrad +4 more
doaj +1 more source
Effect of platelet rich plasma in non surgically treated chronic Achilles tendon ruptures
Foot & Ankle Surgery: Techniques, Reports & Cases, 2023 Background: Achille's tendon ruptures are relatively common among foot and ankle injuries. They are considered chronic when last beyond 4-6 weeks from the time of injuries.
Paolo Lorenzon, MD +2 more
doaj +1 more source
Animals, 2022 This study aimed at evaluating the relationship between biomarkers of oxidative stress (OS) in seminal plasma and sperm motility in bulls before and after cryopreservation. Three ejaculates per bull were collected from 20 young bulls.
Veronica Vigolo +6 more
doaj +1 more source
Tumor Infiltrating Lymphocyte Expression of PD-1 Predicts Response to Anti-PD-1/PD-L1 Immunotherapy [PDF]
Journal of Immunotherapy and Precision Oncology, 2022 Introduction: Many studies have focused on the role of programmed death receptor ligand 1 (PD-L1) expression in predicting immunotherapy outcomes. Limited clinical data are available regarding the role of programmed death receptor 1 (PD-1; the PD-L1 ...
Nicholas J. Bevins +5 more
doaj +1 more source
Frontiers in Immunology, 2022 Primary pulmonary lymphoepithelioma-like carcinoma (PLELC) is an Epstein–Barr virus (EBV)-related, rare subtype of non-small-cell lung cancer (NSCLC). Immune checkpoint inhibitors (ICI) show durable responses in advanced NSCLC. However, their effects and
Yu-Min Zhong +34 more
doaj +1 more source