Results 111 to 120 of about 676,789 (144)

Molecular Imaging of PD-1 Unveils Unknown Characteristics of PD-1 Itself by Visualizing “PD-1 Microclusters”

Programmed cell death-1 (PD-1) is one of the most famous coinhibitory receptors that are expressed on effector T cells to regulate their function. The PD-1 ligands, PD-L1 and PD-L2, are expressed by various cells throughout the body at steady state and their expression was further regulated within different pathological conditions such as tumor-bearing
Wataru, Nishi, Ei, Wakamatsu, Hiroaki, Machiyama, Ryohei, Matsushima, Yosuke, Yoshida, Tetsushi, Nishikawa, Hiroko, Toyota, Masae, Furuhata, Hitoshi, Nishijima, Arata, Takeuchi, Makoto, Suzuki, Tadashi, Yokosuka   +11 more
openaire   +2 more sources

PD-1–PD-1 ligand interaction contributes to immunosuppressive microenvironment of Hodgkin lymphoma

Blood, 2008
AbstractProgrammed death-1 (PD-1)–PD-1 ligand (PD-L) signaling system is involved in the functional impairment of T cells such as in chronic viral infection or tumor immune evasion. We examined PD-L expression in lymphoid cell lines and found that they were up-regulated on Hodgkin lymphoma (HL) and several T-cell lymphomas but not on B-cell lymphomas ...
Ryo, Yamamoto, Momoko, Nishikori, Toshio, Kitawaki, Tomomi, Sakai, Masakatsu, Hishizawa, Masaharu, Tashima, Tadakazu, Kondo, Katsuyuki, Ohmori, Masayuki, Kurata, Takamasa, Hayashi, Takashi, Uchiyama   +10 more
openaire   +2 more sources

Glucocorticoids and PD-1

Science Signaling, 2018
Signaling by the glucocorticoid receptor in NK cells induces expression of the checkpoint inhibitor PD-1 to prevent immunopathology.
openaire   +1 more source

Targeting PD-1

Science Signaling, 2018
Loss of an E3 ubiquitin ligase that targets PD-1 for degradation leads to inefficient antitumor responses by T cells.
openaire   +1 more source

Pretreatment CD8+PD-1+ to CD4+PD-1+ ratio is associated with the prognosis of advanced melanoma patients treated with PD-1 inhibitors

Melanoma Research
The aim of this study was to determine whether the pretreatment CD8+PD-1+ to CD4+PD-1+ (PERLS) ratio is an independent risk prognostic factor of advanced melanoma patients. We retrospectively analyzed the efficacy and flow cytometry data from advanced melanoma patients who received PD-1 inhibitor as monotherapy between January 1, 2018 and January 26 ...
Yao, Gao, Yao, Wang, Yueyue, Luo, Yong, Zhang, Saiqi, Wang, Xiance, Tang, Peng, Qin, Benling, Xu, Quanli, Gao, Tiepeng, Li   +9 more
openaire   +2 more sources

PD-1 takes control

Nature Immunology, 2023
openaire   +2 more sources

PD-1

1997
A. Neil Barclay, Marion H. Brown, S.K. Alex Law, Andrew J. McKnight, Michael G. Tomlinson, P. Anton van der Merwe   +5 more
openaire   +1 more source

PD-1 ANTIBODIES

2017
BARUAH HEMANTA, CHEN CHENG, LIU XIAOLIN, TSUN ANDY, YU DECHAU M   +4 more
openaire   +8 more sources

PD-1 ANTIBODIES

2019
TSUN ANDY, CHEN CHENG, LIU XIAOLIN, YU DE-CHAO MICHAEL   +3 more
openaire   +2 more sources

Anti-PD-1 Antibodies

2016
AMIRINA NAJMIA, CHAMARTHI HAREESH, CHIU MARIA ISABEL, DOTY DANIEL, FENG BIN, JONCA ALEKS, MCQUADE THOMAS, NGUYEN ANHCO, RANGANATH SHEILA, SCHEUPLEIN FELIX, SPAULDING VIKKI A, WANG LEI, WATKINS-YOON JENNIFER   +12 more
  +15 more sources