6ER-033 Pembrolizumab and atezolizumab as possible equivalent first-line therapeutic alternatives in PD-L1-expressing triple-negative breast cancer [PDF]
, 2023 MD Rivas Rodríguez +4 more
openalex +1 more source
PD-L1 is not constitutively expressed on tasmanian devil facial tumor cells but is strongly upregulated in response to IFN-gamma and can be expressed in the tumor microenvironment [PDF]
, 2016 The devil facial tumor disease (DFTD) is caused by clonal transmissible cancers that have led to a catastrophic decline in the wild Tasmanian devil (Sarcophilus harrisii) population.
Corcoran, L. +7 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro +4 more
wiley +1 more source
Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma [PDF]
, 2017 Background Immune checkpoint inhibitors targeting programmed cell death 1 (PD1) or its ligand (PD-L1) showed activity in several cancer types. Methods We performed immunohistochemistry for CD3, CD8, CD20, HLA-DR, phosphatase and tensin homolog (PTEN), PD-
Berghoff, Anna Sophie +16 more
core
Prognostic value of PD-L1 expression on tumor cells combined with CD8+ TIL density in patients with locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy. [PDF]
, 2020 BACKGROUND/AIM:mmune checkpoint inhibition (CPI) has an increasing impact in the multimodal treatment of locally advanced non-small cell lung cancer (LA-NSCLC). Increasing evidence suggests treatment outcome depending on tumor cell PD-L1 expression.
Belka, Claus +11 more
core +1 more source
PD-L1, Galectin-9 and CD8+ tumor-infiltrating lymphocytes are associated with survival in hepatocellular carcinoma [PDF]
, 2017 Novel systemic treatments for hepatocellular carcinoma (HCC) are strongly needed. Immunotherapy is a promising strategy that can induce specific antitumor immune responses.
Beuers, U. (Ulrich) +19 more
core +1 more source
Thermal Processing Creates Water‐Stable PEDOT:PSS Films for Bioelectronics
Advanced Materials, Volume 37, Issue 13, April 2, 2025.Instead of using chemical cross–linkers, it is shown that PEDOT:PSS thin films for bioelectronics become water‐stable after a simple heat treatment. The heat treatment is compatible with a range of rigid and elastomeric substrates and films are stable in vivo for >20 days.
Siddharth Doshi +16 more
wiley +1 more source
Heterogeneous tumor‐immune microenvironments between primary and metastatic carcinoid tumors differentially respond to
, 2020 Shinya Sakata +9 more
openalex +1 more source
Characterisation of novel lung cancer cell lines for immuno-inhibitory markers [PDF]
The present study investigates the expression of immune biomarkers, PD-L1 and HLA-1 on novel lung cancer cell lines (H838, H838-EGFR, A549, A549-ALK, HCC 827, NCI 1650, TWIT, Jacket). PD-L1 and HLA-1 characterisation were initially performed and analysed
Cross, Neil +2 more
core
Lack of PD-L1 Expression by iNKT Cells Improves the Course of Influenza A Infection [PDF]
, 2013 There is evidence indicating that invariant Natural Killer T (iNKT) cells play an important role in defense against influenza A virus (IAV). However, the effect of inhibitory receptor, programmed death-1 (PD-1), and its ligands, programmed death ligand ...
Akbari, Omid +9 more
core +3 more sources