Results 191 to 200 of about 264,642 (338)
PD-1 receptor (PDCD1; PD-1; CD279); programmed cell death 1 ligand 1 (CD274 molecule; PD-L1; B7-H1) [PDF]
, 2010 openalex +1 more source
Advanced Science, EarlyView.Here, it is revealed that ovarian cancer cells release extracellular vesicles enriched with eIF4E, which alters protein production in macrophages. This leads to increased expression of 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase (HMGCR), boosting cholesterol synthesis and activating an immunosuppressive pathway through X‐box binding protein 1 and ...
Sonam Mittal +15 more
wiley +1 more source
Nanoparticle Delivery of Mycophenolic Acid Upregulates PD-L1 on Dendritic Cells to Prolong Murine Allograft Survival [PDF]
, 2011 Anushree C. Shirali +6 more
openalex +1 more source
Advanced Science, EarlyView.Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance +17 more
wiley +1 more source
Advanced Science, EarlyView.Tan et al. developed a platelet membrane‐coated, thermoresponsive liposome for targeted, light‐controlled delivery of fluorinated peptides that promotes programmed death‐ligand 1 degradation, induces tumor immunogenic cell death, suppresses solid tumors and metastases, and triggers durable immune memory, offering a promising strategy for peptide‐based ...
Manman Tan +19 more
wiley +1 more source
Flow cytometric phenotyping of diverse human cancer cell lines for immunological biomarkers expression [PDF]
The tumour microenvironment contains a variety of distinct factors that inhibit the immune system and can cause drug resistance. Some of these factors include the expression of cell surface markers which interact directly with immune cells.
Cross, Neil +3 more
core
PD‐L1 co‐stimulation contributes to ligand‐induced T cell receptor down‐modulation on CD8 + T cells [PDF]
, 2011 Katarzyna Karwacz +6 more
openalex +1 more source
Advanced Science, EarlyView.Spatial transcriptomic analysis of Anaplastic thyroid carcinoma (ATC)‐differentiated thyroid carcinoma (DTC) coexisting tumors reveals that coexisting DTC regions with ATC‐like genomic alterations undergo sequential transcriptomic reprogramming and immune microenvironment remodeling, ultimately evolving into a full ATC pathological phenotype.
Kang Ning +19 more
wiley +1 more source