Results 211 to 220 of about 264,642 (338)

Tumor‐Targeted FABP5/STING Cascade Promote Radiofrequency Ablation Induced Ferroptosis and Intratumoral Immune Rewiring in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Targeted FABP5 co‐delivery nanoparticles amplify RFA‐induced ferroptosis and intratumoral immune rewiring via STING/TBK1 pathway activation in HCC. The pH‐responsive lipid nanoshell was integrated with cyclic RGD peptide (cRGD) and red blood cell membrane (RBCM), and encapsulated with superparamagnetic iron oxide (SPIO) and sgFABP5 to construct FS@RBCM/
Bufu Tang, Xiaojie Zhang, Yiting Sun, Jinhua Luo, Qiaoyou Weng, Cong Zhang, Zilin Wang, Shiji Fang, Yangrui Xiao, Liyun Zheng, Jianfei Tu, Rongfang Qiu, Yang Yang, Zhongwei Zhao, Weiqian Chen, Minjiang Chen, Jiansong Ji   +16 more
wiley   +1 more source

Activation of PD-1/PD-L1 immune checkpoint by Zika virus. [PDF]

PLoS Pathog
Wang C, Xie Y, Li W, Ong CP, Ding H, Yuan S, Cheng G, Jin DY, Ye ZW.   +8 more
europepmc   +1 more source

Targeting HDAC and PARP Enhances STING‐Dependent Antitumor Immunity in STING‐Deficient Tumor

Advanced Science, EarlyView.
Dual HDAC and PARP inhibition restores STING signaling, enhances interferon response, and boosts antitumor immunity in STING‐deficient tumors. . Abstract The stimulator of interferon genes (STING)‐mediated innate immune pathway plays an important role in tumor immunosurveillance.
Chengzhou Mao, Weiwen Fan, Jiaqi Liu, Fangzhou Yang, Wenkai Li, Lulu Li, Zhichao Shi, Qinyuan Li, Zigao Yuan, Yuyang Jiang, Bizhu Chu   +10 more
wiley   +1 more source

The PD-1/PD-L1 pathway and Epstein-Barr virus. [PDF]

Eur J Med Res
Wang H, Zhang N, Xu R, Ji C, Wei Y, Mi Q.   +5 more
europepmc   +1 more source

PD-L1 co-stimulation, ligand-induced TCR down-modulation and anti-tumor immunotherapy [PDF]

, 2012
Katarzyna Karwacz, Frederick Arce, Christopher Bricogne, Grazyna Kochan, David Escors   +4 more
openalex   +1 more source

A Novel Self‐Regulated, Non‐Directional Magnetic Thermos‐Brachytherapy 125I Seed Enhances Anticancer Efficacy by Rescuing Immune Escape

Advanced Science, EarlyView.
This work constructs magnetic nanoparticles (MNPs) and incorporates them with silver rods coated with 125I to form a novel composite seed, which exhibits direction‐independent and self‐regulated heating efficiency, as well as the capacity of preventing MNPs leakage and enabling repeated hyperthermia.
Bin Xu, Ye‐Ming Wu, Yi‐Fei Cheng, Lei Dong, Shuai‐Wen Ding, Sheng‐Rong Chen, Bin‐Da Chen, Ren‐Peng Yang, Wei‐Hua Zhang, Ya‐Jie Wang, Wei‐Pu Mao, Fan Shi, Zhi‐Cheng Jin, Jian‐Jian Chen, En‐Qi Qiao, Yu‐Qing Wang, Jin‐Ze Li, Peng Zeng, Cheng‐Wei Wu, Wei Zhang, Jin‐Bing Xie, Jian Lu, Gao‐Jun Teng   +22 more
wiley   +1 more source

Targeting PD-L1 for PCNS-DLBCL: from molecular effects to clinical translation. [PDF]

Front Immunol
Cao J, Xiong S, Zhang S, Yue N, Wu C.
europepmc   +1 more source

Interpretable Multimodal Fusion Model Enhances Postoperative Recurrence Prediction in Gastric Cancer

Advanced Science, EarlyView.
An interpretable multimodal fusion model (RSA) integrating clinical, radiomic, and pathomic features is developed and validated to predict early postoperative recurrence in gastric cancer. The RSA model demonstrates superior predictive performance and holds potential for guiding adjuvant chemotherapy decisions and improving individualized patient ...
Ping'an Ding, Jiaxuan Yang, Sheng Chen, Honghai Guo, Jiaxiang Wu, Haotian Wu, Li Yang, Wenqian Ma, Yuan Tian, Renjun Gu, Lilong Zhang, Ning Meng, Xiaolong Li, Zhenjiang Guo, Yueping Liu, Lingjiao Meng, Qun Zhao   +16 more
wiley   +1 more source

IGM-7354, an Immunocytokine with IL15 Fused to an Anti-PD-L1 IgM, Induces NK and CD8+ T cell-Mediated Cytotoxicity of PD-L1-Positive Tumor Cells. [PDF]

Cancer Immunol Res
Desbois M, Giffon T, Yakkundi P, Denson CR, Sekar K, Hart KC, Santos D, Calhoun SE, Logronio K, Pandey S, Ng D, Saini AK, Wang BT, Keyt BA, Sinclair AM, Kotturi MF.   +15 more
europepmc   +1 more source

Urinary Cell Levels of mRNA for OX40, OX40L, PD-1, PD-L1, or PD-L2 and Acute Rejection of Human Renal Allografts

, 2010
Cheguevara Afaneh, Thangamani Muthukumar, Michelle Lubetzky, Ruchuang Ding, Catherine Snopkowski, Vijay K. Sharma, Surya V. Seshan, Darshana Dadhania, Joseph E. Schwartz, Manikkam Suthanthiran   +9 more
openalex   +1 more source