Results 221 to 230 of about 276,897 (341)

Directed evolution-driven reprogramming of PD-L1 for compact and tunable checkpoint modulation. [PDF]

J Biol Eng
Ha JY, Kim D, Jebamani P, Park SW, Kim YS, Lee SG, Jung ST.   +6 more
europepmc   +1 more source

Data from Targeting PD-1 or PD-L1 in Metastatic Kidney Cancer: Combination Therapy in the First-Line Setting

, 2023
David H. Aggen, Charles G. Drake, Brian I. Rini   +2 more
openalex   +1 more source

Pneumatically‐Actuated Liquid Metal‐Based Frequency Reconfigurable Antenna

Advanced Science, EarlyView.
A look at a flexible, frequency‐tuning antenna A Soft Solution: Introducing a new antenna design made with liquid metal composites. A Full Package: Combining flexible antennas with pneumatic actuators. End‐to‐End Control: Automatic reconfiguration according to signal strength.
Yiwen Song, Aditya Bharambe, Dinesh K. Patel, Barbara Zhuo, Mason Zadan, Carmel Majidi, Swarun Kumar   +6 more
wiley   +1 more source

Supplementary Figure 2 from PD-L1 Studies Across Tumor Types, Its Differential Expression and Predictive Value in Patients Treated with Immune Checkpoint Inhibitors

, 2023
Harriet M. Kluger, Christopher R. Zito, Gabriela Turcu, Marina K. Baine, Hongyi Zhang, Adebowale Adeniran, Mario Sznol, David L. Rimm, Yuval Kluger, Lieping Chen, Justine V. Cohen, Lucia B. Jilaveanu   +11 more
openalex   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

PD-L1 expression and soluble PD-L1 production in gastric cancer

PD-L1 expression and soluble PD-L1 production in gastric cancer
研究科: 千葉大学大学院医学薬学府（先端医学薬学専攻） 学位記番号 ...
openaire  

Surface‐Associated Proteins on Extracellular Vesicles Remodel the Tumor Microenvironment by Potentiating TGF‐β Signaling in a Contact‐Dependent Manner

Advanced Science, EarlyView.
Extracellular vesicles (EVs) released from TGF‐β‐activated CAFs are enriched with ECM proteins such as TSG6 and THBS1, which facilitate their binding to recipient cell membranes. This EV–cell interaction promotes the clustering of CD44 and TGF‐β receptors on the target cell surface, thereby potentiating TGF‐β signaling activity. This study highlights a
Chao Li, Agustin Enciso‐Martinez, Lizhe Zhu, Sarah A. Rotman, Peter A. van Veelen, Roman I. Koning, Hailiang Mei, Peter ten Dijke   +7 more
wiley   +1 more source

Peripheral blood biomarkers for predicting response to PD-1/PD-L1 inhibitors. [PDF]

Biomark Res
Chen S, Hu Y, Cheng H, Guo S, Han Y, Li K.   +5 more
europepmc   +1 more source

Functional, Pharmacogenomic, and Immune Landscapes of Long Non‐Coding RNAs in Cancer

Advanced Science, EarlyView.
A systematic analysis of 33 cancer types reveals widespread associations between lncRNAs and cancer pathways, drug responses, immune features, and immunotherapy outcomes. The study identifies key lncRNAs linked to therapeutic response and adverse events and introduces PILNC, an interactive web portal for exploring the functional, pharmacogenomic, and ...
Runhao Wang, Mei Luo, Yuan Liu, Jingwen Yang, Yamei Chen, Chengxuan Chen, Lifei Ma, Stephanie Ding, James Wengler, Yong Zang, Bora Lim, Wenbo Li, Liuqing Yang, Chunru Lin, Lixia Diao, Leng Han   +15 more
wiley   +1 more source

Immunotherapy for Glioblastoma: A Focus on PD-1/PD-L1 Inhibitors. [PDF]

Cancers (Basel)
Zoi V, Galani V, Sioka C, Alexiou GA, Kyritsis AP.   +4 more
europepmc   +1 more source