Results 311 to 320 of about 276,897 (341)

Tractable mouse TNBC models capture the heterogeneous tumor immune microenvironment and adaptation to PD-L1 blockade. [PDF]

NPJ Breast Cancer
Salembier R, De Haes C, Demeyere K, Van Laere S, Cervenkova L, Van Renne N, Sotiriou C, Meyer E, Steenbrugge J.   +8 more
europepmc   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

Transforming Growth Factor-β1 as a Biomarker of Malignant Behavior and PD-L1 Expression in Thymic Epithelial Tumors. [PDF]

Cancer Sci
Nakazono C, Okada S, Tando S, Ishihara S, Shimomura M, Furuya T, Kameyama K, Küffer S, Müller D, Marx A, Teramukai S, Ströbel P, Itoh K, Inoue M.   +13 more
europepmc   +1 more source

Immunomodulatory Fibrous Scaffold with Dual Enzyme‐Mimic Activities Prevents Postsurgical Tumor Recurrence

Advanced Science, EarlyView.
A MnOx nanozyme‐functionalized electrospun fibrous scaffold is developed for postoperative therapy by leveraging its intrinsic physicochemical and immunomodulatory properties. Integrating POD‐ and CAT‐like activities, the scaffold induces immunogenic cell death, alleviates hypoxia, and reverses immunosuppression, while simultaneously recruiting and ...
Xiaoyi Zhao, Zhuolong Jiao, Yue Wang, Huimeng Gu, Longfei Li, Jian Song, Chen Xu, Jiajia Xue, Fu‐Jian Xu, Nana Zhao   +9 more
wiley   +1 more source

Association of PD-L1 expression with systemic immune parameters in non-small cell lung cancer. [PDF]

Transl Lung Cancer Res
Gwin ME, von Itzstein MS, Liu J, Fattah FJ, Mu-Mosley H, SoRelle JA, Bhalla S, Dowell JE, Rashdan S, Park JY, Yang DM, Xie Y, Gerber DE.   +12 more
europepmc   +1 more source

Anionic Liposomes as Optimal Membrane Fusion Carriers Enabling in Situ Multiplexed Detection of Extracellular Vesicle MicroRNAs

Advanced Science, EarlyView.
A novel strategy for in situ multiplexed miRNA analysis of plasma extracellular vesicles (EValarm) has been developed. EValarm enables straightforward detection of different extracellular vesicle miRNAs from plasma samples through systematic screening of liposome surface charges, without requiring complex pretreatment steps, and achieves satisfactory ...
Jing‐Yuan Ma, Xiao Wang, Yuhan Cai, Guancheng Wang, Mingze Lu, Kaizheng Feng, Ying Zhao, Xue Wu, Xiaoping Zhang, Haoan Wu, Wei Yu, Ming Ma, Zheng Ge, Yu Zhang   +13 more
wiley   +1 more source

ETV4-Mediated PD-L1 Upregulation Promotes Immune Evasion and Predicts Poor Immunotherapy Response in Melanoma. [PDF]

Oncol Res
Zhu T, Wei T, Yang M, Xu J, Jiang H, He W, Zheng J, Dai H.   +7 more
europepmc   +1 more source

The PD-1/PD-L1 pathway and Epstein-Barr virus. [PDF]

Eur J Med Res
Wang H, Zhang N, Xu R, Ji C, Wei Y, Mi Q.   +5 more
europepmc   +1 more source

Statins attenuate PD-L1 sorting to small extracellular vesicles dependent on ubiquitin-like 3 modification. [PDF]

Sci Rep
Ageta H, Shimada Y, Nagaoka T, Takenaka K, Yoshioka Y, Konno K, Amemiya R, Nagase K, Hitachi K, Onouchi T, Watanabe M, Ochiya T, Tsuchida K.   +12 more
europepmc   +1 more source

Hypoxia-activated paclitaxel prodrugs enable PD-L1 degradation to potentiate cancer chemo-immunotherapy. [PDF]

J Nanobiotechnology
Zhou S, Zhang Q, Han H, Chen G, Wang P, Xue S, Pei Q, Xie Z, Meng X.   +8 more
europepmc   +1 more source