Results 331 to 340 of about 276,897 (341)
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PD-L1 status in breast cancer

Arkhiv patologii, 2019
To investigate the expression of PD-L1 in triple-negative and luminal B, HER2-negative breast carcinoma and to assess the association of the tumor PD-L1 status with the prognosis of the disease.The PD-L1-status of primary tumor was studied in 72 patients with breast cancer, by using an immunohistochemical method.Differences were found in the incidence ...
G A, Frank   +8 more
openaire   +2 more sources

Beyond inhibition against the PD-1/PD-L1 pathway: development of PD-L1 inhibitors targeting internalization and degradation of PD-L1

RSC Medicinal Chemistry
This review clarifies the evolution of PD-L1 inhibitors and provides insights into the current development of PD-L1 inhibitors, especially targeting internalization and degradation of PD-L1.
Jiazheng Guo   +5 more
openaire   +2 more sources

PD-1/PD-L1 in Disease

Immunotherapy, 2017
Expression of PD-1 on T/B cells regulates peripheral tolerance and autoimmunity. Binding of PD-1 to its ligand, PD-L1, leads to protection against self-reactivity. In contrary, tumor cells have evolved immune escape mechanisms whereby overexpression of PD-L1 induces anergy and/or apoptosis of PD-1 positive T cells by interfering with T cell receptor ...
Kuol, Nyanbol   +3 more
openaire   +3 more sources

PD-L1 on pain

Science Signaling, 2017
As well as being an immunosuppressive checkpoint, the tumor-associated cell surface molecule PD-L1 suppresses pain signaling in sensory neurons.
openaire   +1 more source

[PD-L1 expression and PD-1/PD-L1 inhibitors in breast cancer].

Bulletin du cancer, 2018
The development of immune checkpoints inhibitors represents one of the major recent advances in oncology. Monoclonal antibodies directed against the programmed cell death protein 1 (PD-1) or its ligand (PD-L1) provides durable disease control, particularly in melanoma, lung, kidney, bladder and head and neck cancers.
Audrey, Monneur   +2 more
openaire   +1 more source

PD-L1/2: ???????????????????????? ???????????????? ?? ??????????????????

2019
???????? ????????????: ???????????? ???????????????? ???????????????????? ???????? ???????????????????????????? ???????????????? ?????????????????? ???????????? PD-L1/2 (program death ligand) ???? ???????????????? ???????????????????? ???????????????????????? (????) ?????????????? ?????????????????????? ???? ??????????????????????. ?????????????????? ??
openaire   +1 more source

Mitochondrial PD-L1 modulates cancer immunotherapy

Cell Research, 2023
Xiaoming Dai, Jing Liu, Wenyi Wei
openaire   +2 more sources

Ventana PD-L1 Assay

Biomedical Safety & Standards, 2023
openaire   +1 more source

Expression of PD-L1 in mastocytosis

Journal of the American Academy of Dermatology, 2016
Lawrence F. Kuklinski, Jinah Kim
openaire   +2 more sources

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