PD-1/PD-L1, PD-1/PD-L2, and other co-inhibitory signaling pathways in transplantation [PDF]
Transplant International, 2008 Transplantation of cells, tissues and vascularized solid organs is a successful therapeutic intervention for many end-stage chronic diseases. The combination of co-stimulatory blockade with the delivery of negative signals to T cells through co-inhibitory receptors would provide a robust approach to modulating T-cell receptor signaling and improving ...
Río González, María Luisa del +4 more
openaire +5 more sources
Green Processing and Synthesis, 2013 This paper reports palladium (Pd)-containing nanoparticle (NP) formation in nanoporous hypercrosslinked polystyrene (HPS), using Pd acetate as a precursor.
Doluda Valentin Y. +9 more
doaj +1 more source
Bis[μ-bis(diphenylphosphino)methane-К²P:P’]bis[(saccharinato-КN)- palladium(I)] dichloromethane solvate [PDF]
, 2002 The dimeric palladium(I) saccharinate complex [Pd₂(sac)₂(dppm)₂], has been characterized as its di¬chloro¬methane solvate, i.e. [Pd₂(C₇H₄NO₃S)₂(C₂₅H₂₂P₂)₂]•CH₂Cl₂.
Chung, Dong C. +2 more
core +2 more sources
CTLA-4 and PD-1 ligand gene expression in epithelial thyroid cancers [PDF]
, 2018 The dysregulation of PD-1 ligands (PD-L1 and PD-L2) and CTLA-4 ligands (CD80 and CD86) represents a tumor strategy to escape the immune surveillance. Here, the expression of PD-L1, PD-L2, CD80 and CD86 was evaluated at mRNA level in 94 patients affected ...
Antonelli, Alessandro +15 more
core +3 more sources
Pd/Pt IMBALANCE IN LAVAS AND INTRUSIONS OF THE NORILSK-TALNAKH ORE REGION
Геодинамика и тектонофизика, 2021 The paper considers the Pd/Pt ratio in the ores of the Norilsk-1 and Talnakh deposits associated with the Permian-Triassic intrusions of the Norilsk type in comparison with that in the lavas of the same age in the Norilsk region.
T. V. Dudkin +3 more
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Acting without being in control: Exploring volition in Parkinson's disease with impulsive compulsive behaviours. [PDF]
, 2017 BACKGROUND: Several aspects of volitional control of action may be relevant in the pathophysiology of impulsive-compulsive behaviours (ICB) in Parkinson's disease (PD).
de Boer, L +6 more
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The impact of motor symptoms on self-reported anxiety in Parkinson's disease [PDF]
, 2017 OBJECTIVE: Anxiety is commonly endorsed in Parkinson's disease (PD) and significantly affects quality of life. The Beck Anxiety Inventory (BAI) is often used but contains items that overlap with common PD motor symptoms (e.g., “hands trembling”). Because
Cronin-Golomb, A. +3 more
core +1 more source
Expression of TIM3/VISTA checkpoints and the CD68 macrophage-associated marker correlates with anti-PD1/PDL1 resistance: implications of immunogram heterogeneity. [PDF]
, 2020 Although immunotherapies have achieved remarkable salutary effects among subgroups of advanced cancers, most patients do not respond. We comprehensively evaluated biomarkers associated with the "cancer-immunity cycle" in the pan-cancer setting in order ...
Dressman, Devin +13 more
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Potent antitumor antibiotic complex: PD 114,759, PD 115,028, PD 119,707, and PD 119,193.
The Journal of Antibiotics, 1985 Four novel antitumor antibiotics (PD 114,759, PD 115,028, PD 119,707 and PD 119,193) are produced as a complex by a new species of Actinomadura. The proposed name for the culture is Actinomadura verrucosospora subsp. veractimyces ATCC 39363. The antibiotics are extremely bioactive, with MIC values of less than 0.006 ng/ml against several bacteria and ...
J B, Tunac +4 more
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CLINICAL ASPECTS OF SLEEP DISORDERS IN PATIENTS WITH PARKINSON’S DISEASE
Клиническая практика, 2017 According to the scientific literature of sleep disturbance in patients with Parkinson’s disease meet from 51 to 85 %. In this study, PD patients with sleep disturbances were found in 50.1% (348 of 694 patients) were included in the registry (it surveyed
O A Andrienko
doaj +1 more source