Results 91 to 100 of about 326,099 (315)

The young person’s guide to the PDB

Postępy Biochemii, 2016
The Protein Data Bank (PDB), created in 1971 when merely seven protein crystal structures were known, today holds over 120,000 experimentally-determined three-dimensional models of macromolecules, including gigantic structures comprised of hundreds of thousands of atoms, such as ribosomes and viruses.
Wladek, Minor, Zbigniew, Dauter, Mariusz, Jaskolski   +2 more
openaire   +3 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

P2.05 CENTRAL HEMODYNAMIC PARAMETERS AND ARTERIAL STIFFNESS IN PAGET’S DISEASE

Artery Research, 2009
Background: Paget’s disease of bone (PDB) is a common disorder characterised by increased, disorganised bone turnover in affected areas with overgrowth of immature woven bone.
L. D’Elia, G. Mossetti, C.M. McEniery, D. Rendina, B.J. McDonnell, F. Galletti, P. Strazzullo   +6 more
doaj   +1 more source

X-ray Diffraction Data for PDB ID 8VWR. Steroid Hydratase from Comamonas testosteroni

<p>X-ray diffraction data used for the structrual determination of steroid hydratase from Comamonas testosteroni, deposited in the PDB with the ID 8VWR.</p ...
Forrester, T.J.B., Seah, S.Y.K., Schroeter, K.L., Kimber, M.S.   +3 more
core   +1 more source

PDB files for exercise Structural superposition of PDB structures

, 2019
PDB files for exercise Structural superposition of PDB structures, the files have been downloaded from the PDB database and slightly adapted for easier resuse in the ...
Alexander Botzki, Alexander Botzki (6091931)   +1 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Boron/Difluoroamino (B/NF₂) Composites Prepared Through an Energetic Fluorinated-Centerd Surface Modification Strategy to Enhance Their Ignition and Combustion Characteristics

Nanomaterials
To enhance the ignition and combustion characteristics of boron (B), in this study, a suitable, energetic fluorinated group (NF2) that can improve energy and promote combustion efficiency was utilized and B/NF2 composites (B/PDB) with three different ...
Junqi He, Jing Lv, Yanan Li, Wenfang Zheng, Renming Pan   +4 more
doaj   +1 more source

Impact of the Protein Data Bank Across Scientific Disciplines

Data Science Journal, 2020
The Protein Data Bank archive (PDB) was established in 1971 as the 1st open access digital data resource for biology and medicine. Today, the PDB contains >160,000 atomic-level, experimentally-determined 3D biomolecular structures.
Zukang Feng, Natalie Verdiguel, Luigi Di Costanzo, David S. Goodsell, John D. Westbrook, Stephen K. Burley, Christine Zardecki   +6 more
doaj   +1 more source

Homology modeling pdb files

, 2022
Pdb files generated by Phyre 2 from coding sequences for soluble and non-soluble TLR5 in Atlantic Salmon and Rainbow Trout.
Elizabeth Ramirez (12218378), Xiaolu Tang (12218348), delbert vasquez (12218459), Brandon Lofts (12218375)   +3 more
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source