Results 121 to 130 of about 381,553 (352)
PDB files of NOD1 proteins found and downloaded via PHYRE2 ...
Emily Wallace (12218363) +3 more
core +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
P2.05 CENTRAL HEMODYNAMIC PARAMETERS AND ARTERIAL STIFFNESS IN PAGET’S DISEASE
Background: Paget’s disease of bone (PDB) is a common disorder characterised by increased, disorganised bone turnover in affected areas with overgrowth of immature woven bone.
L. D’Elia +6 more
doaj +1 more source
Introduction: Paget disease of bone (PDB) is a disorder of altered bone remodeling mainly characterized by increased osteoclastic activity. While the exact Indian prevalence remains unknown, a clustering of published cases suggests South Indian ...
Adlyne R Asirvatham +6 more
doaj +1 more source
X-ray Diffraction Data for PDB ID 8VWR. Steroid Hydratase from Comamonas testosteroni
<p>X-ray diffraction data used for the structrual determination of steroid hydratase from Comamonas testosteroni, deposited in the PDB with the ID 8VWR.</p ...
Forrester, T.J.B. +3 more
core +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
To enhance the ignition and combustion characteristics of boron (B), in this study, a suitable, energetic fluorinated group (NF2) that can improve energy and promote combustion efficiency was utilized and B/NF2 composites (B/PDB) with three different ...
Junqi He +4 more
doaj +1 more source
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source

