Results 61 to 70 of about 431 (193)

scRNA‐Seq in Gastric Cancer Reveals Macrophage‐Derived C1q as a Diagnostic Marker

open access: yesCancer Science, EarlyView.
Single‐cell sequencing of GC analyzed the tumor microenvironment and discovered the C1QA+ TAMs subpopulation with immunosuppressive function. The role of C1q in the prognosis and diagnosis of GC was demonstrated through plasma and tumor tissue from the GC cohort.
Saisai Gong   +6 more
wiley   +1 more source

Hammersmith Infant Neurological Examination for early detection of cerebral palsy in Ethiopia: A feasibility and knowledge translation study

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
The Hammersmith Infant Neurological Examination (HINE) can be successfully implemented in low‐resource tertiary care settings. Paediatric residents facilitated the implementation of HINE. Early detection of cerebral palsy and referral at an average age of 10.6 months in Ethiopia were achieved.
Selamenesh Tsige Legas   +8 more
wiley   +1 more source

DEVELOPMENT OF ROCK CUTTING TOOL WITH PDC CUTTERS

open access: yesИзвестия Томского политехнического университета: Инжиниринг георесурсов, 2020
Relevance. When developing a tool for drilling wells for various purposes, the main optimization criteria are the increase in mechanical speed and its resource. This is especially true for rock cutting tools intended for drilling in changing geological conditions of deep and inclined wells.
Vyacheslav V. Neskoromnykh   +2 more
openaire   +1 more source

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar   +15 more
wiley   +1 more source

A Literature Review on Non-planar PDC Cutter

open access: yesInternational Journal of Mechanical and Electrical Engineering
Since the introduction of PDC bits in 1973, significant advancements have been achieved in drilling efficiency. However, to address the diverse requirements of various formation rocks—such as differences in hardness, strong abrasiveness, and heterogeneity—and to further enhance drilling performance, several companies worldwide have continuously ...
Lian Chen, Zhiqiang Fu
openaire   +1 more source

Differential Functional Connectivity Between Hippocampus and Prefrontal Cortex Is Associated With Heterogeneity in Open Field Exploration and Is Disrupted Following Maternal Immune Activation

open access: yesHippocampus, Volume 36, Issue 5, September 2026.
ABSTRACT A common paradigm in behavioral neuroscience involves recording neural activity from freely moving rodents as they forage in an open field. This procedure is often used in studies investigating spatial navigation, where recording is conducted in regions such as the hippocampus and entorhinal cortex.
Robert G. K. Munn   +3 more
wiley   +1 more source

New Progress and Future Development of PDC Bit

open access: yesShiyou jixie, 2016
A series of new PDC bits have been developed in foreign countries in order to raise rock breaking efficiency, extend bit service life and reduce trips, drilling cycle and drilling cost.
Pan Jun, Wang Minsheng, Guang Xinjun
doaj  

Digital Health Interventions to Improve Medication Adherence Among Older Adults: A Systematic Review

open access: yesAustralasian Journal on Ageing, Volume 45, Issue 3, September 2026.
ABSTRACT Objective To review evidence on the type, characteristics and effect of digital health interventions (DHIs) on medication adherence among older people. Methods Articles were searched from inception to May 2025 in PubMed, Embase, CINAHL, Scopus and Web of Science.
Kaleab Taye Haile   +7 more
wiley   +1 more source

Finite element modelling of rock mass cutting by cutters for PDC drill bits

open access: yesPetroleum Exploration and Development, 2015
A finite element model of the process of polycrystalline diamond compact (PDC) drill bit cutters cutting rocks was built, and the rock linear and circular cutting processes for different shapes of PDC drill bit cutters were simulated.
T O Pryhorovska   +2 more
doaj   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 30, 14 August 2026.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano   +11 more
wiley   +1 more source

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