Results 41 to 50 of about 47,748 (185)
An Experimental and Numerical Simulation Study on Rock Cutting Based on Pre-Breaking
Shiyou jixie, 2019 The design of the mixed-cutter placement can only rely on the engineering experience. The combination of experiment and numerical simulation is used to study the rock breaking force and rock breaking efficiency of the PDC cutter under different pre ...
Liu Zhong, Hou Huihui, Hu Wei
doaj
Advanced Science, EarlyView.The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English +9 more
wiley +1 more source
Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer
Advanced Science, EarlyView.Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang +17 more
wiley +1 more source
PDC cutter wear and temperature modeling
, 2020 Since Polycrystalline Diamond Compact (PDC) drill bits have been developed, they have made a strong introduction into the drilling industry due to their tendency to produce a higher rate of penetration (ROP) than that of a rollercone.
Bridges, Douglas
core
Cutting Test Device for PDC Bit with Mixed Cutter Arrangement
Shiyou jixie, 2019 The existing PDC bit single-cutter test device is very inconvenient to adjust the parameters such as single-cutter rake angle. It is necessary to carry out frequent replacement of multiple sets of tools, which is not suitable for the mixed cutting ...
Liu Zhong +3 more
doaj
ABAQUS-Based Parameterized Cutter Layout and Rock Breaking Simulation of PDC Bits
Shiyou jixie, 2020 In recent years, structures and types of PDC bits undergone significant changes, which puts forward higher requirements on cutter layout design. As reasonable cutter layout is the key to ensure the drilling life of PDC bits, a parameterized cutter layout
吴泽兵 +4 more
doaj
Real‐Time Monitoring of Mass and Mechanical Properties in Single Cells and Multicellular Spheroids
Advanced Science, EarlyView.This study introduces photothermally actuated microcantilevers combined with optical microscopy to simultaneously measure morphology, mass, and mechanical properties of cellular systems in real‐time. The findings link cytoplasm‐dominated mechanical energy dissipation to the Q‐factor as a novel biophysical parameter.
Ilaria Incaviglia +8 more
wiley +1 more source
, 2017 Most traditional polycrystalline diamond compact (PDC) cutting elements have a flat polycrystalline diamond table at the end of cylindrically shaped tungsten carbide body.
Bradley Krough +9 more
core +1 more source
Structure Design of Bionic PDC Cutter and the Characteristics of Rock Breaking Processes
, 2023 The rational structural design of polycrystalline diamond compact (PDC) cutters effectively enhances the performance of drill bits in rock fragmentation and extends their service life.
Zebing Wu +4 more
core +1 more source
PDC cutter pressure on plastic-brittle rock in the process of its destruction [PDF]
, 2020 Presently, there are no methods for calculating the parameters of the drilling practices with rock-cutting tools equipped with polycrystalline diamond composite (PDC cutters). To create such a method requires the studying their work. The article presents
Hamzja I. Akchurin, Oleg B. Trushkin
core +1 more source